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ORIGINAL CONTRIBUTIONS
  
Year : 1990  |  Volume : 56  |  Issue : 2  |  Page : 127-129

Organisms causing pyoderma and their susceptibility patterns

RG Baslas, SK Arora, RD Mukhija, L Mohan, UK Singh 
 

Correspondence Address:
R G Baslas


Abstract

Five hundred and seventy cases of pyoderma were studied clinically and bacteriologically. Of these, 58.8% cases were of primary pyoderma, and the rest were secondary pyoderma. Primary pyoderma consituted impetigo contagiosa (21.4%), bullous impetigo (3.3%), ecthyma (4.4%), superficial folliculitis (12.3%), chronic folliculitis of legs (8.8%); forunculosis (3.7%) carbuncle (1.8%), folliculitis decalvans (0.4%), sycosis barbae (0.4%) and abscess (2.5%). Secondary pyderma cases were infected scabies (23.9%), infected wound (1.1%), infectious eczematoid dermatitis (12.6%), intertrigo (0.4%) and miscellaneous (3.3%). In 85 samples, no organism was isolated. Out of 485 samples, 75.9% grew a single organism and the rest (24.1%) gave multiple organisms. Among the 603 strains collected, 73.6% were staphylococcus aureus, 25.0% were beta-haemolytic streptococcus and 0.7% each were alpha-haemolytic streptococcus and Gram negative bacilli. Eighty eight per cent strains of Staphylococcus aureous were susceptible to cephaloridine and 27.4% to ampicillin while 97.4% beta haemolytic streptococcus were susceptible to cephaloridine and 23.2% to pencillin.



How to cite this article:
Baslas R G, Arora S K, Mukhija R D, Mohan L, Singh U K. Organisms causing pyoderma and their susceptibility patterns.Indian J Dermatol Venereol Leprol 1990;56:127-129


How to cite this URL:
Baslas R G, Arora S K, Mukhija R D, Mohan L, Singh U K. Organisms causing pyoderma and their susceptibility patterns. Indian J Dermatol Venereol Leprol [serial online] 1990 [cited 2020 Jul 8 ];56:127-129
Available from: http://www.ijdvl.com/text.asp?1990/56/2/127/3502


Full Text

Pyodermas are still quite common in India. Bacteriology of pyodermas has been studied in several other regions,[1],[2],[3],[4],[5],[6],[7],[8],[9],[10] but none is avail­able from our region. We have undertaken this study to find out if there are any differences in the types of bacteria responsible for pyodermas and their susceptibility to antimicrobials.

 Materials and Methods



We studied 570 patients attending our hospi­tal between August 1986 and October 1988. Patients having taken antimicrobial treatment (local or systemic) during the last 7 days were not included. Material collected from the lesions was inoculated in 10% sheep's blood agar and incubated aerobically at 37°C for 24 hours. The organisms grown were identified on the basis of their morphology, cultural charac­teristics and biochemical reactions as per stan­dard methods.[11] Antimicrobial susceptibility was tested on Mueller-Hinton agar for staphy­lococci, and for streptococcus haemolyticus blood agar on Mueller-Hinton base was used, employing disc diffusion technique. The anti­microbial soaked discs were manufactured by M/S Span Diagnostic, Surat.

 Results



Out of 570 patients, 369 (64.7%) were males and 201 (35.3%) were females. Age distribution was 340 (59.7%) below 10 years, 104 (18.2%) between 11-20 years, 70(12.3%) 21-30 years, 27(4.7%) 31-40 years, 13(2.3%) 41-50 years and 16(2.8%) above 50 years.

In 85 samples, no organism could be isola­ted. Single organism was isolated from 368 (75.9%) samples, while from 117(24.1%) samples more than one type of organisms were isola­ted. Organisms isolated from different types of pyoderma are given in [Table 1].

Susceptibility pattern of Staphylococcus aureus (SA) and beta-haemolytic streptococcus (BHS) to different antimicrobials is given in [Table 2]. Other organisms isolated were not studied for susceptibility pattern.

 Comments



We found male preponderance as observed by others[1],[2],[3] except Ramani and Jayakar[4] who noticed female preponderance. Like other studies[1],[4] maximum (340,59.7%) cases were below 10 years of age. Only Bhaskaran et al[2] have reported maximum cases in the 11-30 years age group.

Isolation rate (91.5%) of SA both alone and in combination was similar to some workers[7],[8].

while other studies [1],[2],[3],[6],[7],[8],[9],[10] subhave found lower figures. Isolation rate (31.1 %) of BHS both alone and in combination was similar to Kar et at,[5] while others [1],[2],[3],[6],[7],[9],[10] subhave shown variable results (12% to 89%)

Both SA and BHS were highly susceptible to cephaloridine and gentamicin. Least suscep­tibility was seen to penicillin and ampicillin [Table 2]. Other workers[2],[3],[4],[5] have also shown high (95% or more) susceptibility to gentamicin but they have not studied susceptibility to cephaloridine. Majority of workers[2],[3],[4],[5] have shown least susceptibility of SA to penicillin and moderate to high (50% to 100%) suscepti­bility of BHS to penicillin. Susceptibility patterns of SA to ampicillin in other studies[2],[3],[4],[5] were variable (12% to 88%), and for BHS were more than 70 %. Susceptibility of both the organisms to erythromycin was moderate [Table 2] while other studies[1],[2],[4],[5] have shown high (more than 94%) susceptibility to erythromycin. Other studies[3],[5] have shown a variable susceptibility pattern (high to moderate) to co-trimoxazole, while we found only moderate susceptibility.

Cephalexin was found to be moderately effec­tive, but there are no previous studies on this drug.

References

1Kandhari KC, Prakash 0 and Singh G : Bacterio­logy of pyodermas, Ind J Dermatol Venereol, 1962; 28 :125-133.
2Bhaskaran CS, Rao PS, Krishnamurthy T et al Bacteriological study of pyoderma, Ind J Dermatol Venereol Leprol, 1979; 45 : 162-170.
3Khare AK, Bansal NK and Dhruv AK : A clinical and bacteriological study of pyodermas, Ind J Dermatol Venereol Leprol, 1988; 54 192-195.
4Ramani TV and Jayakar PA : Bacteriological study of 100= cases of pyodermas with special reference to staphylococci, their antibiotic sensiti­vity and phage pattern, Ind J Dermatol Venereol Leprol, 1980; 46 : 282-286.
5Kar PK, Sharma NP and Shah BH : Bacterio­logical study of pyoderma in children, Ind J Der­matol Venereol Leprol, 1985; 51 : 325-327.
6Pasricha A, Bhujwala RA and Shriniwas : Bacterio­logical study of pyoderma, Ind J Pathol Bacteriol, 1972; 15 : 131-138.
7Lamont IC : Local antibiotics in skin infections, Brit J Dermatol, 1959; 71 : 201-210.
8Ghosh B, Gupta M and Bhattacharya SR : Clinico­bacteriological study of pyoderma, Ind J Dermatol, 1974; 19 :35-38.
9Verma KC, Chugh TD and Bhatia KK : Strepto­cocci in pyoderma, Ind J Dermatol Venereol Leprol, 1981; 47 : 202-207.
10Anthony BF, Perlman LV and Wannamaker LW Skin infections and acute nephritis- in American Indian children, Paediat, 1967; 39 :.263-276.
11Cruickshank R, Duguid JP,Marmion-BP et at Medical Microbiology, 12th ed, Churchill Living­stone, Edinburgh, 1974.

 

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