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CASE REPORT
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A new presentation of isolated cutaneous Rosai-Dorfman disease: Eruptive xanthoma-like lesions


1 Department of Dermatology, Andrology and STDs, Mansoura University, Mansoura, Egypt
2 Department of Dermatology, Andrology and STDs, Port Said University, Port Said, Egypt

Correspondence Address:
Mohammed Fawzy El-Kamel,
Department of Dermatology, Andrology and STDs, Mansoura University, Mansoura, 35516
Egypt
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdvl.IJDVL_540_17

PMID: 30333358

Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a benign lympho-histiocytic proliferative disorder initially described with bilateral painless lymphadenopathy (90 %), fever, leukocytosis, elevated ESR, anemia, and polyclonal hypergammaglobulinemia (90 %). Extranodal forms occur in 43% of cases, the skin being the most common site. Around 10% of patients have skin lesions and in 3%, the disease is limited exclusively to the skin. Here, we report a male patient who presented with pure cutaneous lesions which mimic eruptive xanthoma clinically. However, the diagnosis was established histo pathologically. So, high level of clinical suspension is critical to avoid missing such cases.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow