IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 117 
     Home | Feedback | Login
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  NAVIGATE here  
     Search
     Current Issue
     Submit Article 
     My Preferences 
     Dermatology crossword 

 


Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
   Table of Contents - Current issue
Coverpage
November-December 2014
Volume 80 | Issue 6
Page Nos. 493-592

Online since Friday, November 07, 2014

Accessed 7,806 times.

PDF access policy
Full text access is free in HTML pages; however the journal allows PDF access only to users from INDIA and paid subscribers.

EPub access policy
Full text in EPub is free except for the current issue. Access to the latest issue is reserved only for the paid subscribers.
View as eBookView issue as eBook
Author Institution MappingAuthor Institution Mapping
Access StatisticsIssue statistics
RSS FeedRSS
Hide all abstracts  Show selected abstracts  Export selected to  Add to my list
EDITORIALS  

Dermatoscope-the dermatologist's stethoscope  Highly accessed article p. 493
Aimilios Lallas, Giuseppe Argenziano
DOI:10.4103/0378-6323.144141  PMID:25382503
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

The trials of treating warts  Highly accessed article p. 495
Sam Gibbs
DOI:10.4103/0378-6323.144142  PMID:25382504
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
THERAPEUTIC GUIDELINES Top

Photochemotherapy (PUVA) in psoriasis and vitiligo  Highly accessed article p. 497
Shrutakirthi D Shenoi, Smitha Prabhu
DOI:10.4103/0378-6323.144143  PMID:25382505
Phototherapy with photochemotherapy (PUVA) is a well-known and well-studied modality for the treatment of psoriasis, which involves systemic or topical administration of chemicals known as psoralens and administration of ultraviolet light in increasing dosages after requisite time gap. PUVA is also used in the treatment of widespread vitiligo with moderately good results, though it is being surpassed by ultraviolet B (UVB), which is equally or slightly more efficacious with fewer side effects. PUVA induces repigmentation by varying mechanisms such as stimulation of melanogenesis, immunomodulation and activation of growth factors, though the exact mechanism is still speculative. There are various studies evaluating the efficacy of PUVA in psoriasis as well as in vitiligo, either alone or in combination with other immunosuppressants like azathioprine and calcipotriene.
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
ORIGINAL ARTICLES Top

The utility of dermoscopy in the diagnosis of evolving lesions of vitiligo p. 505
Sarvesh S Thatte, Uday S Khopkar
DOI:10.4103/0378-6323.144144  PMID:25382506
Background: Early lesions of vitiligo can be confused with various other causes of hypopigmentation and depigmentation. Few workers have utilized dermoscopy for the diagnosis of evolving lesions of vitiligo. Aim: To analyze the dermoscopic findings of evolving lesions in diagnosed cases of vitiligo and to correlate them histopathologically. Methods: Dermoscopy of evolving lesions in 30 diagnosed cases of vitiligo was performed using both polarized light and ultraviolet light. Result: On polarized light examination, the pigmentary network was found to be reduced in 12 (40%) of 30 patients, absent in 9 (30%), and reversed in 6 (20%) patients; 2 patients (6.7%) showed perifollicular hyperpigmentation and 1 (3.3%) had perilesional hyperpigmentation. A diffuse white glow was demonstrable in 27 (90%) of 30 patients on ultraviolet light examination. Melanocytes were either reduced in number or absent in 12 (40%) of 30 patients on histopathology. Conclusion: Pigmentary network changes, and perifollicular and perilesional hyperpigmentation on polarized light examination, and a diffuse white glow on ultraviolet light examination were noted in evolving vitiligo lesions. Histopathological examination was comparatively less reliable. Dermoscopy appears to be better than routine histopathology in the diagnosis of evolving lesions of vitiligo and can obviate the need for a skin biopsy.
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Intralesional immunotherapy with killed Mycobacterium indicus pranii vaccine for the treatment of extensive cutaneous warts p. 509
Saurabh Singh, Kavish Chouhan, Somesh Gupta
DOI:10.4103/0378-6323.144145  PMID:25382507
Background: Multiple cutaneous warts in adults are often symptomatic, cosmetically disabling, and difficult to treat. Killed Mycobacterium indicus pranii (previously known as Mycobacterium w, popularly known as Mw) vaccine has earlier been investigated in genital warts with encouraging results. Objective: To evaluate the efficacy and safety profile of intralesional injected killed Mw vaccine for the treatment of extensive extragenital cutaneous warts. Methods: In this study, a retrospective analysis of medical records was performed in patients with cutaneous warts treated with intralesional Mw vaccine. Only patients with more than 5 extra-genital warts, involving at least two body sites and which had not shown any signs of spontaneous regression over 6 months were treated with the vaccine. Results: Forty four patients were treated with intralesional Mw vaccine. The mean number of warts was 41.5 ± 25.7 with a disease duration of 3.1 ± 2.5 years. Complete clearance was achieved in 24 (54.5%) patients with a mean of 3.4 ± 1.1 intralesional injections. Cosmetically acceptable response to therapy (>75% clearance) was achieved in 37 (84.1%) patients. Wart response at distant sites was seen in 38 (86.3%) patients. Thirty-six patients (81.8%) experienced mild therapy-related side effects. Eighteen patients with complete response were followed up for 5.27 ± 1.7 months and none had recurrence of lesions. Conclusions: Killed Mw vaccine is safe and effective in the treatment of extensive cutaneous warts. Larger, preferably randomized controlled trials are needed to assess its efficacy vis a vis standard therapies for warts.
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Safety and effectiveness of autoinoculation therapy in cutaneous warts: A double - blind, randomized, placebo - controlled study p. 515
Niharika Ranjan Lal, Amrita Sil, Tirthankar Gayen, Debabrata Bandyopadhyay, Nilay Kanti Das
DOI:10.4103/0378-6323.144146  PMID:25382508
Background: In spite of the availability of multiple treatment options, viral warts are known for their persistence and recurrence, causing frustration to patients and treating physicians. Aims: To study the effectiveness and safety of autoinoculation as a treatment modality in cutaneous warts. Methods: A double-blind, placebo-controlled study was carried out. In the treatment group, full-thickness warty tissue was excised, minced and implanted in a small dermal pocket. In the control group, warty tissue was only excised and not implanted, though a dermal pocket was made. Patients were evaluated every four weeks with lesion counts. The procedure was repeated at 4 and 8 weeks. Response was assessed at each visit and at 12 weeks. Results: Forty-eight patients with cutaneous warts (male: female = 32:16) were randomized into autoinoculation and control groups. The number of warts at baseline was comparable in both groups (P = 0.293). Reduction in the number of warts was significantly more in the autoinoculation group (8.50 ± 13.88) than in the control group (10.04 ± 5.80) from 8 weeks onwards (P = 0.010). Complete resolution occurred only in the autoinoculation group, in 62.5% of cases. Adverse effects were seen in 11 patients, including infection of the donor site (5 cases), keloid formation (3) and hypopigmentation (3). Conclusion: Autoinoculation may be an effective therapeutic modality for cutaneous warts and two sessions may be required for optimum results.
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

The effectiveness of finasteride and dutasteride used for 3 years in women with androgenetic alopecia p. 521
Ids H Boersma, Arnold P Oranje, Ramon Grimalt, Matilde Iorizzo, Bianca M Piraccini, Emiel H Verdonschot
DOI:10.4103/0378-6323.144162  PMID:25382509
Background: The effectiveness of finasteride and dutasteride in women with androgenetic alopecia has been the subject of debate. Aim: To evaluate the effectiveness of finasteride and dutasteride on hair loss in women with androgenetic alopecia over a period of 3 years. Methods: From a database containing systematically retrieved data on 3500 women treated for androgenetic alopecia between 2002 and 2012 with finasteride 1.25 mg or dutasteride 0.15 mg, a random sample stratified for age and type of medication was taken to yield 30 women in two age categories: below and above 50 years, and for both medications. Hair thickness of the three thinnest hairs was measured from standardized microscopic images at three sites of the scalp at the start of the treatment and after 3 years of continuous medication intake. The macroscopic images were evaluated independently by three European dermatologists/hair experts. The diagnostic task was to identify the image displaying superior density of the hair. Results: Both age categories showed a statistically significant increase in hair thickness from baseline over the 3-year period for finasteride and dutasteride (signed rank test, P = 0.02). Hair thickness increase was observed in 49 (81.7%) women in the finasteride group and in 50 (83.3%) women in the dutasteride group. On average, the number of post-treatment images rated as displaying superior density was 124 (68.9%) in the finasteride group, and 118 (65.6%) in the dutasteride group. Dutasteride performed statistically significantly better than finasteride in the age category below 50 years at the central and vertex sites of the scalp. Conclusions: Finasteride 1.25 mg and dutasteride 0.15 mg given daily for 3 years effectively increased hair thickness and arrested further deterioration in women with androgenetic alopecia.
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
CASE REPORTS Top

Peripheral T-cell lymphoma at the injection site of influenza vaccination p. 526
Xin-ling Bi, Yan-fang Liu, Miao-xia He, Jun Gu
DOI:10.4103/0378-6323.144165  PMID:25382510
Pseudolymphomas or B-cell lymphoma at the vaccination site have been reported by several authors. However, onset of cutaneous T-cell lymphoma with cytotoxic features is a rare complication of vaccination. We report a 27-year-old man who developed a nodule and ulcer that arose at the site of injection of influenza vaccine. The neoplastic cells reacted positively for CD56, CD3, CD2, perforin, and granzyme B, but negatively for CD4, CD8, CD10, CD19, CD30, CD34, CD79, and betaF1. Molecular studies showed T-cell receptor γ (TCR-γ) chain monoclonal rearrangement. A diagnosis of peripheral T-cell lymphoma, not otherwise specified (NOS) was established. The patient had high fever, progressive liver dysfunction and a rapid fatal evolution.
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Co-existence of extramammary Paget's disease and Bowen's disease of vulva p. 530
Tarang Goyal, Anupam Varshney, Ranjan Solanki
DOI:10.4103/0378-6323.144170  PMID:25382511
Extramammary Paget's disease and Bowen's disease are histologically similar and immunohistochemistry is often required to make the diagnosis. We present a case of vulval Paget's disease with Bowen's disease in an elderly female. Strong positivity for cytokeratin 7, anti CAM 5.2, carcinoembryonic antigen (CEA) and periodic acid-Schiff (PAS) stain in clitoral, left labial and interface regions of the vulvectomy specimen confirmed the diagnosis of Paget's disease (PD) while positive staining for p63 in the right labial and interface regions helped in establishing the diagnosis of concurrent Bowen's disease (BD).
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Eccrine syringofibroadenomatosis of the reactive subtype occurring in chronic poorly-controlled psoriasis p. 534
Yee Kiat Heng, Jiun Yit Pan, Suat Hoon Tan, Hong Liang Tey
DOI:10.4103/0378-6323.144172  PMID:25382512
Eccrine syringofibroadenomatosis (ESFA) is a rare adnexal tumor with acrosyringeal differentiation. Clinically, it can be mistaken for granulomatous infections or malignancies such as squamous cell carcinoma. Despite the rarity of the condition, we recently encountered two cases of the reactive subtype, which occurred in patients with poorly controlled chronic psoriasis. Both patients presented with long-standing, thick verrucous lesions on the lower legs. The diagnosis was made after histological examination and exclusion of infectious and neoplastic disorders. As this is a reactive disorder, management is focused on treating the underlying condition. Unfortunately, psoriasis was difficult to manage in both our patients and they defaulted further treatment. It is important to recognize ESFA as it can be confused with infectious or malignant disorders.
[ABSTRACT]  [HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
IMAGES IN CLINICAL PRACTICE Top

Rhinophyma-like cutaneous leishmaniasis p. 537
Monia Youssef, Yosra Soua, Hichem Belhadjali
DOI:10.4103/0378-6323.144175  PMID:25382513
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
LETTERS TO THE EDITOR Top

Clinical spectrum and antimicrobial resistance pattern of skin and soft tissue infections caused by community acquired-methicillin resistant Staphylococcus aureus p. 539
JK Veni Emilda, Shalini M Shenoy, M Chakrapani, Pramod Kumar, K Gopalkrishna Bhat
DOI:10.4103/0378-6323.144178  PMID:25382514
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Ipsilateral galactorrhea following zoster of the T4 dermatome p. 540
Nidhi Jindal, VK Jain, Sameer Aggarwal, Sarabjit Kaur
DOI:10.4103/0378-6323.144181  PMID:25382515
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Beard involvement in a man with frontal fibrosing alopecia p. 542
Rafael Salido-Vallejo, Gloria Garnacho-Saucedo, Jose Carlos Moreno-Gimenez, Francisco M Camacho-Martinez
DOI:10.4103/0378-6323.144183  PMID:25382516
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Bullous pemphigoid clinically presenting as lichen amyloidosis p. 544
Projna Biswas, Ishad Aggarwal, Debashis Sen, Atoka Sumi, Arghyaprasun Ghosh
DOI:10.4103/0378-6323.144184  PMID:25382517
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Recurrent blisters in a case of resolving Stevens-Johnson syndrome/toxic epidermal necrolysis p. 546
Yao-Nien Chuang, Yin-Yu Ho, Tsu-Man Chiu
DOI:10.4103/0378-6323.144187  PMID:25382518
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Multiple cutaneous mastocytomas p. 547
Taru Garg, Ram Chander, Niti Gaur, Aashim Singh, Anita Nangia
DOI:10.4103/0378-6323.144189  PMID:25382519
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Dyschromatosis symmetrica hereditaria with neurological abnormalities p. 549
Abhijit Dutta, Sudip Kumar Ghosh, Rajesh Kumar Mandal
DOI:10.4103/0378-6323.144191  PMID:25382520
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Localized purpuric lesions in a case of classical pityriasis rosea p. 551
Neha Bhalla, Swagata Tambe, Vijay Zawar, Rajiv Joshi, Hemangi Jerajani
DOI:10.4103/0378-6323.144194  PMID:25382521
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Subcutaneous phaeohyphomycosis caused by Bipolaris hawaiiensis in an immunocompetent patient p. 554
Rajesh Verma, Partho Roy, Biju Vasudevan, Puneet Bhatt, Veena Kharayat, Gagandeep Kaur
DOI:10.4103/0378-6323.144198  PMID:25382522
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Disseminated cutaneous glomuvenous malformation p. 556
Aditi Jha, V Ramesh, Avninder Singh
DOI:10.4103/0378-6323.144200  PMID:25382523
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Pigmented Bowen's disease with prominent amyloid deposition on the eyelid p. 558
Takamichi Ito, Maiko Wada, Yuki Kuma, Makiko Kido-Nakahara, Yuichi Yamada, Shinji Okano, Yoshinao Oda, Masutaka Furue
DOI:10.4103/0378-6323.144204  PMID:25382524
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Adult onset Langerhans cell histiocytosis: Report of two patients p. 560
Indukooru Subrayalu Reddy, Swarnalata Gowrishankar, Vijay Kumar Somani, Dronamraju Buchi Narayana Murthy
DOI:10.4103/0378-6323.144206  PMID:25382525
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Primary cutaneous extranodal natural killer/T-cell lymphoma p. 562
Vijaya Basavaraj, Rashmi Kumararadhya, Sunila , Manjunath Vimala
DOI:10.4103/0378-6323.144209  PMID:25382526
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

NK/T-cell lymphoma nasal type with an unusual clinical course p. 564
Vladimira Radochova, Jakub Radocha, Marketa Nova, David Belada, Radovan Slezak
DOI:10.4103/0378-6323.144213  PMID:25382527
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Malignant melanoma with metastasis to the male breast p. 566
Bong-Su Kang, Seung-Ki Kim
DOI:10.4103/0378-6323.144214  PMID:25382528
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Hidradenocarcinoma of the chest p. 568
Ana Brasileiro, Andre Lencastre, Alexandre Joao, Margarida Apetato
DOI:10.4103/0378-6323.144215  PMID:25382529
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Nodular hidradenoma of the scalp: A cytomorphological evaluation on fine needle aspiration cytology p. 569
Jitendra G Nasit, Gauravi Dhruva
DOI:10.4103/0378-6323.144218  PMID:25382530
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Reversal of pseudo-ainhum with acitretin in Camisa's syndrome p. 572
Mahendra M Kura, Sumit Parsewar
DOI:10.4103/0378-6323.144220  PMID:25382531
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Cold agglutinin disease-associated digital gangrene treated with plasmapheresis p. 575
Yuta Koike, Yuichiro Akiyama, Atsushi Utani
DOI:10.4103/0378-6323.144221  PMID:25382532
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
QUIZ Top

An asymptomatic nodule on the finger p. 577
Prachi G Agrawal, Sunanda A Mahajan, Uday S Khopkar, Vidya D Kharkar
DOI:10.4103/0378-6323.144223  PMID:25382533
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
NET LETTERS Top

H syndrome-Four new patients from India p. 579
Vered Molho-Pessach, Mekhla Varma, Koumudi Godbole, Nutan Kamath, Abraham Zlotogorski
DOI:10.4103/0378-6323.144229  PMID:25382534
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Thyroid dysfunctions in morphoea: A preliminary report  Highly accessed article p. 579
Iffat Hassan, Tasleem Arif, Parvaiz Anwar
DOI:10.4103/0378-6323.144230  PMID:25382535
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Late-onset apocrine chromhidrosis p. 579
Ilgul Bilgin, Kiymet Handan Kelekci, Sevil Catal, Aylin Calli
DOI:10.4103/0378-6323.144231  PMID:25382536
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Concomitant Darier's disease and Sjφgren's syndrome p. 579
Ilteris Oguz Topal, Gulcin Harman Kamali, Gonca Gokdemir, Sule Gungor
DOI:10.4103/0378-6323.144233  PMID:25382537
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta

Lichen planus pigmentosus inversus p. 580
Houda Hammami Ghorbel, Talel Badri, Ehsen Ben Brahim, Samy Fenniche, Rym Benmously, Insaf Mokhtar
DOI:10.4103/0378-6323.144234  PMID:25382538
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
BOOK REVIEW Top

Litt's D.E.R.M Drug Eruptions and Reactions manual, 20 th (Platinum Anniversary) Edition p. 581
Lalit Kumar Gupta
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [Sword Plugin for Repository]Beta
RESIDENTS CORNER Top

Viva questions from the IJDVL p. 583
Vishalakshi Viswanath, Resham Vasani
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [Sword Plugin for Repository]Beta
RETRACTION Top

Cutaneous Paecilomyces lilacinus infections in immunocompromised and immunocompetent patients: Retraction p. 592
M Ramam
DOI:10.4103/0378-6323.144235  PMID:25382539
[HTML Full text]  [PDF]  [Mobile Full text]  [EPub]  [PubMed]  [Sword Plugin for Repository]Beta
Online since 15th March '04
Published by Medknow