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Year : 2018  |  Volume : 84  |  Issue : 5  |  Page : 539--546

Safety of important dermatological drugs (retinoids, immune suppressants, anti androgens and thalidomide) in reproductively active males with respect to pregnancy outcome: A brief review of literature


1 Department of Dermatology, Katihar Medical College, Katihar, Bihar, India
2 Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India
3 Department of Dermatology, ESI-PGIMSR and ESIC Medical College, Kolkata, West Bengal, India
4 Department of Dermatology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
5 Department of Dermatology, CGHS, Kolkata, West Bengal, India

Correspondence Address:
Dr. Anupam Das
Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijdvl.IJDVL_77_17

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Paternally transmitted damage to offspring is recognized as a complex issue. Each parent contributes 23 chromosomes to a child; hence, it is necessary to know the effects of both maternal and paternal pre-and peri-conceptional exposure to drugs on pregnancy outcome. While there are many studies on the effects of maternal drug exposure on pregnancy outcome, literature on paternal exposure is scarce. Of late however, paternal exposure has been receiving increasing attention. We present a brief review on the safety of commonly used drugs in dermatology, focused on retinoids, immune suppressants, anti androgens and thalidomide.






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