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 CASE REPORT
Year : 2017  |  Volume : 83  |  Issue : 6  |  Page : 673--676

Cutaneous plasmacytosis: A rare entity with unique presentation


1 Kolkata Reference Laboratory, SRL Ltd., Aizol, Mizoram, India
2 Department of Dermatology and Venereology, Civil Hospital, Aizol, Mizoram, India
3 Clinical Reference Laboratory, SRL Ltd., Mumbai, Maharashtra, India
4 Department of Pediatric Dermatology, Institute of Child Health, Kolkata, West Bengal, India

Correspondence Address:
Subhra Dhar
Flat 9 C, Palazzo, 35, Panditia Road, Kolkata - 700 029, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijdvl.IJDVL_874_16

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Primary cutaneous plasmacytosis is a rare cutaneous disorder with extensive cutaneous plaques/papules mainly on the trunk and face. Cases have mostly been documented from Japan. We present here a rare case of cutaneous plasmacytosis from India of Mongolian descent. This 50-year-old female from Mizoram had extensive maculo-papular violaceous plaques distributed on the face, axillae, trunk and lower extremities. Initial and repeat skin biopsy revealed dense perivascular and periadnexal mature plasma cells. She also had lymphadenopathy. Serum protein electrophoresis did not reveal any M band and the Bence Jones protein was negative in urine. The patient had multiple superficial lymph nodes and a biopsy from the cervical lymph node showed effacement of normal nodal architecture by sheets of plasma cells. Immuno histochemistry was done from both skin and lymph node biopsies. The kappa and lambda tight chains were not restricted; there by proving the polyclonal nature of the plasma cells. The novelty of the case lies in its classical clinical presentation with histopathological documentation.






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