Indexed with PubMed and Science Citation Index (E) 
Users online: 2614 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
    Next article
    Previous article
    Table of Contents

    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded85    
    Comments [Add]    

Recommend this journal


Year : 2017  |  Volume : 83  |  Issue : 2  |  Page : 200--204

Variables affecting interpretation of skin prick test results

Department of Dermatology, Faculty of Medicine, Çukurova University, Adana, Turkey

Correspondence Address:
Suhan GŁnasti Topal
Department of Dermatology, Faculty of Medicine, Çukurova University, Balcali, Saricam, Adana 01330
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.192956

Rights and Permissions

Background: Both performer- and device-dependent variabilities have been reported in sizes of wheal responses to skin prick tests. Objective: We aimed to evaluate whether or not variabilities in sizes of wheal responses influence the final interpretation of skin prick tests; in other words, the decision on whether or not there is an allergy to a given antigen. Methods: Skin prick tests with positive and negative controls and extracts of Dermatophagoides farinae and Dermatophagoides pteronyssinus were done for 69 patients by two different persons, using two different puncturing devices- disposable 22-gauge hypodermic needles and metal lancets. Results: Among four different skin prick tests, the average coefficients of variation in sizes of wheal responses were near to or higher than 20% for all of them. On the other hand, in the final interpretation of results, kappa values indicated substantial or almost perfect agreements between these tests. However, the frequency of establishing allergy to the house dust mites widely ranged in these tests (20.8–35.8% for D. farinae and 20.8–28.3% for D. pteronyssinus). Limitations: The conduction of the study in a single center and the comparisons of results of only two performers. Conclusion: We feel that variabilities in sizes of wheal responses of skin prick test can influence its categorical results.


Print this article     Email this article

Online since 15th March '04
Published by Wolters Kluwer - Medknow