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 Table of Contents    
IMAGES IN CLINICAL PRACTICE
Year : 2016  |  Volume : 82  |  Issue : 5  |  Page : 583-584

Cutaneous metastasis as the primary manifestation of large cell neuroendocrine carcinoma of lung


1 Department of Dermatology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey, Turkeyxs
2 Department of Dermatology, Haseki Training and Research Hospital, Istanbul, Turkey
3 Department of Dermatology, Medicine Hospital, Istanbul, Turkey

Date of Web Publication4-Aug-2016

Correspondence Address:
Dr. Asli Akin Belli
Orhaniye Mah., Ismet Catak Cad., 48000 Mugla
Turkeyxs
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.171008

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How to cite this article:
Belli AA, Dervis E, Geyik N. Cutaneous metastasis as the primary manifestation of large cell neuroendocrine carcinoma of lung. Indian J Dermatol Venereol Leprol 2016;82:583-4

How to cite this URL:
Belli AA, Dervis E, Geyik N. Cutaneous metastasis as the primary manifestation of large cell neuroendocrine carcinoma of lung. Indian J Dermatol Venereol Leprol [serial online] 2016 [cited 2019 Aug 21];82:583-4. Available from: http://www.ijdvl.com/text.asp?2016/82/5/583/171008


A 55-year-old male presented with asymptomatic, 1 to 3 cm, erythematous nodules on the scalp and beard for a month [Figure 1]a. Our differential diagnoses included lymphoma, pseudolymphoma and cutaneous metastasis. Histopathological examination showed a poorly differentiated metastatic tumor. Immunohistochemical stains were positive for synaptophysin, chromogranin a, cytokeratin 7 and vimentin indicating a metastatic large cell neuroendocrine carcinoma. Chest radiography showed a round opacity in the middle zone of the right lung representing the primary tumour [Figure 1]b. Chemotherapy with cisplatin was initiated but he died 4 months later.
Figure 1: (a) Well-demarcated, erythematous nodules on the scalp and beard area. (b) Chest radiography showing a round opacity in the middle zone of the right lung (arrow)

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