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Year : 2014  |  Volume : 80  |  Issue : 6  |  Page : 530--533

Co-existence of extramammary Paget's disease and Bowen's disease of vulva

1 Departments of Dermatology, Venereology and Leprosy, Muzaffarnagar Medical College and Hospital, Uttar Pradesh, India
2 Department of Pathology, Muzaffarnagar Medical College and Hospital, Uttar Pradesh, India

Correspondence Address:
Tarang Goyal
Department of Dermatology, Muzaffarnagar Medical College and Hospital, Muzaffarnagar - 251 201, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.144170

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Extramammary Paget's disease and Bowen's disease are histologically similar and immunohistochemistry is often required to make the diagnosis. We present a case of vulval Paget's disease with Bowen's disease in an elderly female. Strong positivity for cytokeratin 7, anti CAM 5.2, carcinoembryonic antigen (CEA) and periodic acid-Schiff (PAS) stain in clitoral, left labial and interface regions of the vulvectomy specimen confirmed the diagnosis of Paget's disease (PD) while positive staining for p63 in the right labial and interface regions helped in establishing the diagnosis of concurrent Bowen's disease (BD).


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Online since 15th March '04
Published by Wolters Kluwer - Medknow