IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 4486 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
  
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Article in PDF (1,348 KB)
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
   References
   Article Figures

 Article Access Statistics
    Viewed3378    
    Printed55    
    Emailed1    
    PDF Downloaded90    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 


 
 Table of Contents    
LETTER TO THE EDITOR
Year : 2014  |  Volume : 80  |  Issue : 4  |  Page : 376-378

Hidradenitis suppurativa treated with carbon dioxide laser followed by split skin thickness graft


1 Department of Dermatology, PSG IMSR, Coimbatore, Tamil Nadu, India
2 Department of Plastic Surgery, PSG IMSR, Coimbatore, Tamil Nadu, India
3 Department of General Surgery, PSG IMSR, Coimbatore, Tamil Nadu, India

Date of Web Publication18-Jul-2014

Correspondence Address:
Karthika Natarajan
Department of Dermatology, PSG IMSR, Coimbatore - 641 004, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.136987

Rights and Permissions



How to cite this article:
Natarajan K, Srinivas C R, Thomas M, Aruchamy M, Kumar S R. Hidradenitis suppurativa treated with carbon dioxide laser followed by split skin thickness graft. Indian J Dermatol Venereol Leprol 2014;80:376-8

How to cite this URL:
Natarajan K, Srinivas C R, Thomas M, Aruchamy M, Kumar S R. Hidradenitis suppurativa treated with carbon dioxide laser followed by split skin thickness graft. Indian J Dermatol Venereol Leprol [serial online] 2014 [cited 2019 Sep 16];80:376-8. Available from: http://www.ijdvl.com/text.asp?2014/80/4/376/136987


Sir,

A 34-year-old woman presented with multiple, infected nodules with interconnecting sinuses over the axillae, groin and perianal areas of 6 months duration. The lesions first developed over the left axilla [Figure 1] and gradually spread to the right axilla followed by groin and perianal areas. They were accompanied by pain and purulent discharge. The patient also complained of difficulty in walking and lifting her hands.
Figure 1: Pre-operative image showing nodules, pustules and sinus tracts

Click here to view


On examination, multiple discharging sinuses with surrounding induration were present in the axilla, groin and perianal areas. Complete blood picture revealed low hemoglobin (8 g/dl) and raised erythrocyte sedimentation rate. Peripheral smear was suggestive of normocytic, normochromic anemia with relative neutrophilia. Human immunodeficiency virus and hepatitis B surface antigen assays were negative. An ultrasound examination was done as marsupialization of the sinus tracts was being considered as a possible treatment modality. It showed ill-defined hypoechoic lesions in bilateral axillae, groin, perineal region and mons pubis in the subcutaneous soft tissue planes.

Histopathological examination of a punch biopsy specimen from the left axilla revealed a mixed dermal inflammatory infiltrate of neutrophils, lymphocytes and plasma cells. A sinus tract lined with granulation tissue was noted along with a perifollicular mixed inflammatory infiltrate. Dilated infundibulum filled with keratin and periadnexal inflammation was observed. These findings were consistent with hidradenitis suppurativa.

Pus culture showed a heavy growth of Streptococcus pyogenes. The patient did not respond to multiple courses of oral antibiotics including amoxicillin-clavulanic acid, clindamycin, cefixime and cotrimoxazole. A course of isotretinoin 20-30 mg daily was given for a period of 12 weeks with only slight improvement. Since the patient did not show a significant response to medical management, surgical intervention was planned. A wide excision of the diseased area over the left axilla was performed under general anesthesia using a carbon dioxide laser [Figure 2] and [Figure 3]. Laser ablation was performed in the continuous mode and the energy used varied from 10 to 15 W. Blood vessels were coagulated using the defocused mode. However, as the carbon dioxide laser was not effective in achieving complete hemostasis, diathermy was used to achieve control of bleeding [Figure 4]. Since, the patient was anemic with a pre-operative hemoglobin of 9.6 g/dl, 1 unit of whole blood was transfused in the post-operative period. A split skin thickness graft was performed 10 days following the excision to ensure formation of adequate granulation tissue and successful graft uptake. The patient was treated with hematinics, antibiotics and regular dressing change. One year after surgery, the patient presented with persistent lesions over the right axilla, groin and perianal area but the grafted area in the left axilla was quiescent and showed no new lesions [Figure 5].
Figure 2: Excision of diseased tissue using carbon dioxide laser

Click here to view
Figure 3: Excised tissue

Click here to view
Figure 4: Immediate post-operative appearance of left axilla

Click here to view
Figure 5: Left axilla, 12 months following surgery and grafting

Click here to view


Numerous therapeutic modalities include antibiotics, systemic or intralesional steroids, oral retinoids, cyclosporine, colchicine and dapsone have been used in the treatment of hidradenitis suppurativa. [1]

Surgical removal has been recommended for persistent lesions. Surgical options include radical excision with use of grafts or flaps and exteriorization and deroofing of sinus tracts. Surgical excision using the carbon dioxide laser (10,600 nm) and healing by secondary intention is associated with good results and minimal complications. [2] The advantages of this method are prevention of recurrences, achievement of adequate hemostasis and avoidance of multiple treatment sessions.

No post-operative complications such as scar contracture, graft failure or relapse of disease were encountered. With regard to hemostasis, high flow vessels greater than 500 μm are likely to bleed after carbon dioxide laser whereas without blood flow, vessels up to 2 mm have been coagulated. [3] An additional advantage of using carbon dioxide laser in defocused mode may be the destruction of residual lesions by the heat generated during the procedure.

 
  References Top

1.Hazen PG, Hazen BP. Hidradenitis suppurativa: Successful treatment using carbon dioxide laser excision and marsupialization. Dermatol Surg 2010;36:208-13.  Back to cited text no. 1
    
2.Madan V, Hindle E, Hussain W, August PJ. Outcomes of treatment of nine cases of recalcitrant severe hidradenitis suppurativa with carbon dioxide laser. Br J Dermatol 2008;159:1309-14.  Back to cited text no. 2
    
3.Kauvar AN, George JH. Principles and Practices in Cutaneous Laser Surgery. Boca Raton: Taylor and Francis; 2005.  Back to cited text no. 3
    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5]

This article has been cited by
1 Lasers and Intense Pulsed Light Hidradenitis Suppurativa
Ditte M. Saunte,Jan Lapins
Dermatologic Clinics. 2016; 34(1): 111
[Pubmed] | [DOI]



 

Top
Print this article  Email this article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow