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 ORIGINAL ARTICLE
Year : 2011  |  Volume : 77  |  Issue : 2  |  Page : 148--155

Evaluation of photopatch test allergens for Indian patients of photodermatitis: Preliminary results


1 Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, India
2 Department of Dermatology, Venereology and Leprosy, RPGMC, Kangra (Tanda), Himachal Pradesh, India

Correspondence Address:
Nand Lal Sharma
Department of Dermatology and Venereology, RPGMC, Kangra (Tanda), Himachal Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.77453

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Background: There is a strong need to develop a photopatch test tray suitable for Indian patients of photodermatitis as European/Scandinavian photopatch test trays may not be wholly relevant for them. Aim: We carried out this study using photoallergens relevant in the Indian context to determine their relevance in patients of photodermatitis. Methods: Thirty patients (M:F, 23:7) between 19 and 76 years of age of photodermatitis and 10 controls were patch- and photopatch tested with 20 common photoallergens. In addition, the patients were also (photo) patch tested with articles of daily use as and when these were suspected to be the cause. Results: Forty-three positive reactions to one or more antigens were seen in 22 (74%) patients. Fourteen positive photopatch tests to seven allergens were observed in 10 (33%) patients, and nine (30%) of them had a definite relevance. The most common contact allergen was fragrance mix (FM) (30%), followed by p-phenylenediamine (20%) and Parthenium hysterophorous (17%). The definite relevance of the patch- and photopatch tests could be correlated in 47% of these patients. Conclusions: FM is the most common contact and photocontact allergen among the various photopatch test antigens. Although differences in technique and evaluation make direct comparison between different centers difficult, still photopatch testing remains an integral part and gold standard for the work-up of the photosensitive patients.






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