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ACNE IN INDIA: GUIDELINES FOR MANAGEMENT - IAA CONSENSUS DOCUMENT
Year : 2009  |  Volume : 75  |  Issue : 7  |  Page : 4

Genetics in acne


members Indian Acne Alliance, India

Correspondence Address:
Raj Kubba
Consultant Dermatologist, Kubba Clinic,10, Aradhana Enclave, Ring Road, New Delhi - 110066
India
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Source of Support: Production and publication of this supplement is made possible by an educational grant from Galderma India Pvt. Ltd., Conflict of Interest: Indian Acne Alliance (IAA) meetings logistics to formulate IAA consensus document DQAcne in India: Guidelines for managementDQ were supported by Galderma India Pvt. Ltd.

PMID: 19282581

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How to cite this article:
Kubba R, Bajaj A K, Thappa D M, Sharma R, Vedamurthy M, Dhar S, Criton S, Fernandez R, Kanwar A J, Khopkar U, Kohli M, Kuriyipe V P, Lahiri K, Madnani N, Parikh D, Pujara S, Rajababu K K, Sacchidanand S, Sharma V K, Thomas J. Genetics in acne. Indian J Dermatol Venereol Leprol 2009;75, Suppl S1:4

How to cite this URL:
Kubba R, Bajaj A K, Thappa D M, Sharma R, Vedamurthy M, Dhar S, Criton S, Fernandez R, Kanwar A J, Khopkar U, Kohli M, Kuriyipe V P, Lahiri K, Madnani N, Parikh D, Pujara S, Rajababu K K, Sacchidanand S, Sharma V K, Thomas J. Genetics in acne. Indian J Dermatol Venereol Leprol [serial online] 2009 [cited 2014 Sep 3];75, Suppl S1:4. Available from: http://www.ijdvl.com/text.asp?2009/75/7/4/45471


Although acne is not an inherited condition, there is an inherited predisposition. Several genes are believed to be involved, of which only the gene for cytochrome P-450-1A1 and the gene for steroid 21-hydroxylase are documented.[1] There is high concordance rate among identical twins. [2] XYY karyotype is associated with severe acne. [2] Positive family history of acne is obtained in 40% of patients [3] and correlates with more severe disease.

 
  References Top

1.Herane MI, Ando I. Acne in infancy and acne genetics. Dermatology 2003;206:24-8.  Back to cited text no. 1  [PUBMED]  [FULLTEXT]
2.Degitz K, Placzek M, Borelli C, Plewig D. Pathophysiology of acne. J Dtsch Dermatol Ges 2007;5:316-23.  Back to cited text no. 2    
3.Cunliffe WJ, Gollnick HPM. Acne: Diagnosis and management. London: Martin Dunitz 2001. p. 1-46.  Back to cited text no. 3    




 

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