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Year : 2009  |  Volume : 75  |  Issue : 6  |  Page : 638-

Generalized pustular psoriasis of pregnancy successfully treated with cyclosporine


Department of Dematology, Assam Medical College and Hospital, Dibrugarh, Assam, India

Correspondence Address:
Debeeka Hazarika
Department of Dematology, Assam Medical College and Hospital, Dibrugarh, Assam
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.57743

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Two multigravidae aged 27 and 29 years, with previous uneventful pregnancies, second being psoriatic, reported at 24 and 28 weeks of pregnancies, with generalized pustular lesions. Laboratory findings, including serum calcium were normal. Ultrasonography showed normal fetal growth. Histopathology confirmed pustular psoriasis. Patients were put on cyclosporine 3 mg/ kg weight/ day after failure of an initial systemic steroid. Blood pressure, pulse, and fetal heart sounds were recorded every 12 hours, and ultrasonography and blood parameters, biweekly. Cyclosporine was tapered and stopped after delivery of two healthy babies at 38 weeks. We conclude that cyclosporine can be an option in the management of pustular psoriasis of pregnancy or psoriasis with pustulation in pregnancy.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow