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Year : 2009  |  Volume : 75  |  Issue : 4  |  Page : 437

Asymptomatic yellowish papules and plaques over flexures


Department of Dermatology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India

Date of Web Publication3-Jul-2009

Correspondence Address:
Feroze Kaliyadan
Department of Dermatology, Amrita Institute of Medical Sciences and Research Centre, Elamakkara PO Kochi - 26, Kerala
India
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Source of Support: None, Conflict of Interest: None


PMID: 19584484

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How to cite this article:
Kaliyadan F, Dharmaratnam A D, Jayasree M G, Parmar C. Asymptomatic yellowish papules and plaques over flexures. Indian J Dermatol Venereol Leprol 2009;75:437

How to cite this URL:
Kaliyadan F, Dharmaratnam A D, Jayasree M G, Parmar C. Asymptomatic yellowish papules and plaques over flexures. Indian J Dermatol Venereol Leprol [serial online] 2009 [cited 2019 Jun 26];75:437. Available from: http://www.ijdvl.com/text.asp?2009/75/4/437/53170


A 27-year-old male patient presented to us with progressively increasing asymptomatic-raised skin lesions mainly over both axillae and groins since the age of 4 years. Since then, the area of involvement had increased slowly over the last few years. The patient did not have any other significant systemic and ophthalmic problems. No family member had similar or any other significant/relevant disease. On examination, yellowish papules and plaques were seen mainly over both axillae, sides of chest, groins and medial aspect of thighs [Figure 1]. There were similar lesions scattered over the neck, cubital and popliteal fossae. There were no mucus membrane lesions. Systemic examination was within normal limits. Ophthalmological and cardiac evaluation was done, which was also normal. Investigations including complete blood counts, stool and urine examination, calcium/phosphate levels were all within normal ranges. A skin biopsy was taken. The Orcein stained image is shown [Figure 2].


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1.Wenstrup RJ, Zhao H. Heritable disorders of connective tissue with skin changes. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editors. Fitzpatrick's Dermatology in General Medicine. 6 th ed. New York: McGraw-Hill; 2003:1503-05.  Back to cited text no. 1    
2.Chassaing N, Martin L, Calvas P, Le Bert M, Hovnanian A. Pseudoxanthoma elasticum : a0 clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations. J Med Genet 2005;42:881-92.  Back to cited text no. 2    
3.Katona E, Aslanidis C, Remenyik E, Csikos M, Karpati S, Paragh G, et al . Identification of a novel deletion in the ABCC6 gene leading to Pseudoxanthoma elasticum . J Dermatol Sci 2005;40:115-21.  Back to cited text no. 3    
4.Pfendner EG, Vanakker OM, Terry SF, Vourthis S, McAndrew PE, McClain MR, et al . Mutation detection in the ABCC6 gene and genotype-phenotype analysis in a large international case series affected by pseudoxanthoma elasticum . J Med Genet 2007;44:621-8.  Back to cited text no. 4    
5.Kumar GN, Ragi KV, Nair PS. Pseudoxanthoma elasticum with cerebrovascular accident. Indian J Dermatol Venereol Leprol 2007;73:191-3.  Back to cited text no. 5  [PUBMED]  Medknow Journal


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