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Year : 2009  |  Volume : 75  |  Issue : 4  |  Page : 398--400

Three cases of Dowling Degos disease in two families

1 Department of Skin and STD, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India
2 Department of Skin and STD, PESIMSR, Kuppam, Chittoor Dist, Andhra Pradesh, India

Correspondence Address:
P V Bhagwat
Departments of Skin and STD, Karnataka Institute of Medical Sciences, Hubli - 580 022, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.53139

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Dowling Degos disease is a rare condition inherited as autosomal dominant trait characterized by numerous, asymptomatic, symmetrical, progressive, small, round-pigmented macules over axillae and groins, face, neck, arms and trunk, scattered comedo-like lesions (dark dot follicles) and pitted acneiform scars. Histopathology is diagnostic. We are hereby reporting three cases of Dowling Degos disease belonging to two families. Our first and second case belonged to the same family, whereas our third case belonged to different family. In our series, all the patients had onset after puberty. All three cases had reticulate pigmentation over face and/or flexures, black comedones and follicular pits. On histopathological examination of the skin biopsy taken from the lesion over the back, all these patients showed classical histopathological features of Dowling Degos disease. We feel that one should investigate the patient presenting with reticulate pigmentation over the face and flexures with blackish comedone-like lesions, because histopathological features of this condition are unmistakable.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow