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 CASE REPORT
Year : 2009  |  Volume : 75  |  Issue : 4  |  Page : 394--397

Primary systemic amyloidosis: Three different presentations


Department of Dermatology, Jawaharlal Nehru Medical College, Sawangi, Meghe, Wardha, India

Correspondence Address:
Vikrant Saoji
22 Dandige layout, Shankar Nagar, Nagpur - 440 010
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.53138

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Primary systemic amyloidosis is a rare disease. We report three cases of primary systemic amyloidosis, one case with multiple myeloma and two cases without any hematological abnormality. Purpuric lesions were the only presenting symptoms of the patient with multiple myeloma and only on investigation, myeloma was detected. Bone marrow biopsy and serum and urine electrophoresis were normal in remaining two cases. These two patients presented with typical waxy lesions on face. Cutis verticis gyrata was present in one case and carpal tunnel syndrome was seen in other case as an additional diagnostic clue. Macroglossia was present in all three cases. Diagnosis was confirmed in all three cases by biopsy using haematoxylin and eosin staining and Congo red staining. Polarized microscopy was not done because of unavailability.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow