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Year : 2008  |  Volume : 74  |  Issue : 5  |  Page : 436--446

Therapeutic trials for systemic sclerosis: An update


Department of Dermatology, Maulana Azad Medical College and Lok Nayak Hospital, Delhi, India

Correspondence Address:
Kabir Sardana
466, Sector 28, Noida 201 303, UP
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.44298

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The pathogenesis of systemic sclerosis (SSc) is complex, and the final story is yet to be elucidated. The clinical heterogeneity of the disease, its various autoimmune and antibody profiles, its long course and tendency for spontaneous cure makes the design of clinical trials difficult. The overwhelming need in this disease is to diagnose it early and identify those patients who will benefit most from early, aggressive treatment. We attempt to review data from recent clinical trials and the lessons derived.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow