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 CASE REPORT
Year : 2007  |  Volume : 73  |  Issue : 4  |  Page : 253--256

Type I lepra reaction presenting as immune reconstitution inflammatory syndrome


Department of Dermatology, Seth G. S. Medical College and KEM Hospital, Mumbai, India

Correspondence Address:
Vidya Kharkar
OPD 117, Department of Dermatology, Seth G. S. Medical College and KEM Hospital, Parel, Mumbai - 400012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.33637

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Immune reconstitution inflammatory syndrome (IRIS) is an unusual inflammatory reaction due to infectious and non-infectious causes occurring in human Immunodeficiency virus (HIV)-infected patients. IRIS occurs after the initiation of antiretroviral therapy. There are no reports of type I lepra reaction due to IRIS in published literature from India. We report two cases of HIV-infected males who presented with borderline tuberculoid leprosy in type 1 reaction after the initiation of highly active antiretroviral treatment (HAART). Case 1 presented with multiple, tender, erythematous and hypoesthetic plaques on the trunk and extremities after 3 months of antiretroviral therapy. In case 2, type I lepra reaction was observed 2 months after the initiation of HAART.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow