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Year : 2007  |  Volume : 73  |  Issue : 3  |  Page : 191--193

Pseudoxanthoma elasticum with cerebrovascular accident

1 Department of Pathology, Medical College Hospital, Trivandrum, Kerala, India
2 Department of Dermatology and Venereology, Medical College Hospital, Trivandrum, Kerala, India

Correspondence Address:
G Nanda Kumar
Department of Pathology, Medical College Hospital, Trivandrum - 695 011, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.32746

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A 65-year-old male presented with right hemiparesis and skin lesions. On examination, the patient had multiple, discrete, skin-colored papules on the neck and upper chest with wrinkling of the skin. The lateral part of the trunk and medial aspect of both upper arms showed atrophic plaques. A computerized tomography scan of the head showed dilatation of the basilar artery with a frontoparietal infarct. Funduscopic examination showed characteristic angioid streaks. Skin biopsy of the papule and atrophic plaques showed epidermal atrophy, calcium deposits in the mid-dermis and basophilic clumped and fragmented elastic fibers in the mid- and lower dermis, all findings consistent with pseudoxanthoma elasticum. We are reporting here a case of pseudoxanthoma elasticum with cerebrovascular accident.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow