IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 4625 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Article in PDF (155 KB)
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
   What is your dia...
   Discussion
   References
   Article Figures

 Article Access Statistics
    Viewed3928    
    Printed59    
    Emailed1    
    PDF Downloaded151    
    Comments [Add]    

Recommend this journal

 


 
QUIZ
Year : 2007  |  Volume : 73  |  Issue : 1  |  Page : 63-64

Urticarial papules and plaques on the trunk


1 Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Amrinder Jit Kanwar
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.30662

Rights and Permissions



How to cite this article:
Narang T, Kanwar AJ, Dogra S, Radotra BD. Urticarial papules and plaques on the trunk. Indian J Dermatol Venereol Leprol 2007;73:63-4

How to cite this URL:
Narang T, Kanwar AJ, Dogra S, Radotra BD. Urticarial papules and plaques on the trunk. Indian J Dermatol Venereol Leprol [serial online] 2007 [cited 2019 Oct 18];73:63-4. Available from: http://www.ijdvl.com/text.asp?2007/73/1/63/30662


A 65-year-old female was being treated with cyclophosphamide for follicular dendritic cell tumor of the cervical lymph nodes. She presented to us with erythematous painful eruption on the extremities and trunk that started approximately one week after starting the chemotherapy. She had been treated with chlorpheniramine followed by a course of prednisolone 30 mg OD for one week. This caused resolution of the lesions, but they recurred after the corticosteroids were stopped. The patient was otherwise fit and well with no other symptoms. She was on no other medication. Examination revealed numerous tender, erythematous and edematous papules and plaques on her trunk and proximal parts of extremities [Figure - 1]a and b. Her palms and soles were spared.

Complete blood count, renal and liver function tests, electrolytes and autoantibody screen were normal with the exception of an elevated neutrophil count (12.10 109/L). Skin biopsy taken from one of the lesions showed a polymorphous inflammatory reaction within and around some eccrine sweat ducts, consisting of many neutrophils and a few lymphocytes without red blood cells extravasation [Figure - 2]. Special stains with Perls and Rouge Congo were negative. Acid-fast bacilli, periodic acid-Schiff and Gomori methenamine silver stains and a tissue culture were all negative for infection. Cyclophosphamide was stopped and over the course of the next week, the eruption gradually resolved without any other intervention.


  What is your diagnosis? Top




Click here to view answer. View Answer


 
  References Top

1.Harrist TJ, Fine JD, Berman RS, Murphy GF, Mihm MC Jr. Neutrophilic eccrine hidradenitis. A distinctive type of neutrophilic dermatosis associated with myelogenous leukemia and chemotherapy. Arch Dermatol 1982;118:263-6.  Back to cited text no. 1    
2.Susser WS, Whitaker-Worth DL, Grant-Kels JM. Mucocutaneous reactions to chemotherapy. J Am Acad Dermatol 1999;40:367-98, 399-400.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Bachmeyer C, Aractingi S. Neutrophilic eccrine hidradenitis. Clin Dermatol 2000;18:319-30.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]
4.Greenbaum BH, Heymann WR, Reid CS, Travis SF, Donaldson MH. Chemotherapy-associated eccrine hidradenitis, neutrophilic eccrine hidradenitis reevaluated: The role of neutrophilic infiltration. Med Pediatr Oncol 1988;16:351-5.  Back to cited text no. 4  [PUBMED]  
5.Hurt MA, Halvorson RD, Petr FC Jr, Cooper JT Jr, Friedman DJ. Eccrine squamous syringometaplasia: A cutaneous sweat gland reaction in the histological spectrum of chemotherapy-associated eccrine hidradenitis and neutrophilic eccrine hidradenitis. Arch Dermatol 1990;126:73-7.  Back to cited text no. 5  [PUBMED]  
6.Bilic M, Mutasim DF. Neutrophilic eccrine hidradenitis in a patient with Behcet's disease. Cutis 2001;68:107-11.  Back to cited text no. 6  [PUBMED]  


    Figures

[Figure - 1], [Figure - 2]



 

Top
Print this article  Email this article
Previous article Next article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow