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 CASE REPORT
Year : 2006  |  Volume : 72  |  Issue : 6  |  Page : 449--451

Variant of Vohwinkel's syndrome


Department of Dermatology, Kasturba Medical College Hospital, Attavar, Mangalore, India

Correspondence Address:
Gatha M Upadya
Department of Dermatology, KMC Hospital, Attavar, Mangalore - 575 001
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.29344

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A 28-year-old female born to consanguineous parents, presented with progressive palmoplantar keratoderma since the age of six months and a constricting band on right fourth finger of one year duration. There was history of similar complaints being present in two other family members. Associated clinical findings included starfish-shaped cornified plaques on knuckles, resorption of distal phalanges and keratotic plaques on elbows, groins and knees. The patient was mentally sound and had normal audiometry. Biopsy from hyperkeratotic plaque showed hyperkeratosis, parakeratosis, increased granular layer and papillomatosis. Gene mapping for loricrin mutation was found to be negative.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow