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 CASE REPORT
Year : 2006  |  Volume : 72  |  Issue : 4  |  Page : 300--302

Tuberous sclerosis complex associated with dyschromatosis universalis hereditaria


Department of Dermatology and Venereology, Medical College, Calicut, Kerala, India

Correspondence Address:
M P Binitha
'Haritha' (PO), Beypore, North Calicut - 673 015, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.26729

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Tuberous sclerosis is an autosomal dominant disease due to mutations in two genetic loci, characterized by hamartoma formation in the skin, nervous system, heart, kidney, and other organs. Dyschromatosis universalis hereditaria is an autosomal dominant genodermatosis, characterized by small hyperpigmented and hypopigmented macules, uniformly distributed over the entire body. The face is rarely involved, and the palms, soles, and mucous membranes are usually spared. We report a case of tuberous sclerosis with dyschromatosis universalis hereditaria, with hyperpigmented and hypopigmented macules affecting the palms, soles, and oral mucosa. To our knowledge, this is the first reported case of such an association.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow