IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 4383 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   Article in PDF (143 KB)
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
   Acknowledgment
   References
   Article Figures

 Article Access Statistics
    Viewed5978    
    Printed72    
    Emailed4    
    PDF Downloaded141    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 


 
LETTER TO EDITOR
Year : 2006  |  Volume : 72  |  Issue : 1  |  Page : 60-62

Ultrasound biomicroscopy of the skin to detect a subclinical neuroma of the proximal nail-fold


1 UBM Institute, Dadar, Mumbai, India
2 Consultant Dermatologist, Bandra, Mumbai, India
3 Department of Dermatology, LTMC, Sion, Mumbai, India

Correspondence Address:
Kalpana D Bhatt
UBM Institute, Ganesh Baug, Behind Ruia College, Dadar, Mumbai 400019, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.19725

Rights and Permissions



How to cite this article:
Bhatt KD, Fernandes R, Dhurat R. Ultrasound biomicroscopy of the skin to detect a subclinical neuroma of the proximal nail-fold. Indian J Dermatol Venereol Leprol 2006;72:60-2

How to cite this URL:
Bhatt KD, Fernandes R, Dhurat R. Ultrasound biomicroscopy of the skin to detect a subclinical neuroma of the proximal nail-fold. Indian J Dermatol Venereol Leprol [serial online] 2006 [cited 2019 Jul 20];72:60-2. Available from: http://www.ijdvl.com/text.asp?2006/72/1/60/19725


Sir,

Ultrasound is a very useful, noninvasive modality to visualize normal and abnormal tissue characteristics in situ . Recent advances in transducer technology have led to its application in dermatology.[1],[2] Here, ultrasound is used to measure skin thickness. It gives information on the axial and lateral extension of tumors[3] and inflammatory processes. It can also be used to monitor various inflammatory conditions such as psoriasis, scleroderma, etc, and to study the therapeutic effects of drugs on skin.

Dermatological ultrasound is performed using a 20-MHz probe, giving a resolution of 80 Ám and depth penetration of 8-10 mm. Ultrasound biomicroscopy (UBM) is high-frequency ultrasonography performed using a 50-MHz transducer[4] or probe (the resolution is 40 mm and depth penetration is only 4 mm). In dermatology, UBM gives a better resolution of the dermis and epidermis compared with the lower-frequency probes. We present a case in which a subclinical tumor (neuroma) in the dermis and epidermis of the skin of the proximal nail-fold of the left thumb was detected by performing UBM.

A 35-year-old female presented with gradually increasing excruciating intermittent pain and tingling numbness at the tip of the left thumb since 5 years. There were no aggravating factors. There was no history of trauma or neck pain. Cutaneous examination revealed normal skin on the left thumb [Figure - 1] and no mass or any other abnormality could be palpated. The only positive finding was local tenderness in an area of 2 mm in the region of the proximal nail-fold of the left thumb.

An X-ray of the cervical spine was normal and showed no evidence of spondylosis. A 20-MHz ultrasound of the affected area was indeterminate. Subsequently, UBM was performed. It showed a well-defined hypoechoic mass measuring 350 x 400 Ám in the dermis extending into and causing a breach in the continuity of the overlying epidermis [Figure - 2][Figure - 3]. UBM of the opposite thumb was normal, showing a normal hyperechoic entry echo of the epidermis and a homogenous isoechoic dermis. A diagnosis of glomus tumor of the proximal nail fold was made. Excisional biopsy of the lesion was suggestive of neuroma. The patient is asymptomatic postoperatively.

Neuromas are solitary skin colored or pink firm papules or nodules at the site of trauma or a scar. In mature neuromas, a lancinating pain may be elicited in response to local pressure. Initially, as a routine, a 20-MHz ultrasound was performed. [5],[6],[7],[8] Because the findings were indeterminate, a UBM was performed and showed us a well-defined subclinical tumor.

A non-invasive investigation, UBM, is best suited for epidermal and dermal lesions as its resolution is far superior to that of a 20-MHz ultrasound probe. It exhibits very small anatomical details in the epidermis and dermis because its penetration depth is only 4 mm. Its resolution is comparable with that of a low-power microscope.

Since it is a non-invasive, investigative modality, it can be repeatedly performed with good patient compliance. However, UBM has its limitations in that it does not give tissue diagnosis, which rests on biopsy.


  Acknowledgment Top


We thank Dr. H. R. Jerajani, Professor and Head, Department of Dermatology, LTMC, Sion, Mumbai, for her guidance.

 
  References Top

1.Serup J. Ten years experience with high frequency ultrasound examination of the skin. In: Hoffman K, editor. Ultrasound in Dermatology. 1st ed. Germany: Springer-Verlag; 1992. p. 41-54.   Back to cited text no. 1    
2.Thiboutot D. Dermatological application of high-frequency ultrasound. SPIE Conference Proceedings. 1999. Abstract No. 3664. Available at http://www.bioe.psu.edu/labs/NIH/derm_app. pdf.  Back to cited text no. 2    
3.Breitbart EW, Mohr P. Sonographic structures of benign skin tumors. In: Hoffman K, editor. Ultrasound in Dermatology. 1st ed. Germany: Spinger-Verlag; 1992. p. 171-80.   Back to cited text no. 3    
4.El-Gammal S, Hoffman K, Auer T, Korten M, Atlmeyer P, Hoss A, et al. A 50 MHz high-resolution ultrasound imaging system for dermatology. In : Hoffman K, editor. Ultrasound in Dermatology. 1st ed. Germany: Spinger-Verlag; 1992. p. 297-321.   Back to cited text no. 4    
5.Jovanovic DL, Katic V, Jovanovic B. Value of preoperative determination of skin tumor thickness with 20-MHz ultrasound. Arch Dermatol 2005;141:269-70.  Back to cited text no. 5  [PUBMED]  [FULLTEXT]
6.Chen SH, Chen YL, Cheng MH, Yeow KM, Chen HC, Wei FC. The use of ultrasonography in preoperative localization of digital glomus tumors. Plast Reconstr Surg 2003;112:115-9.  Back to cited text no. 6  [PUBMED]  [FULLTEXT]
7.Hirai T, Fumiiri M. Ultrasonic observation of the nail matrix. Dermatol Surg 1995;21:158-61.  Back to cited text no. 7  [PUBMED]  
8.Ogino T, Ohnishi N. Ultrasonography of a subungual glomus tumour. J Hand Surg 1993;18:746-7.  Back to cited text no. 8  [PUBMED]  


Figures

[Figure - 1], [Figure - 2], [Figure - 3]

This article has been cited by
1 Subcutaneous phaeohyphomycosis caused by cladophialophora boppii
Pereira, R., Nayak, C., Deshpande, S., Bhatt, K., Khatu, S., Dhurat, R.
Indian Journal of Dermatology, Venereology and Leprology. 2010; 76(6): 695-698
[Pubmed]



 

Top
Print this article  Email this article
Previous article Next article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow