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 CASE REPORTS
Year : 2005  |  Volume : 71  |  Issue : 4  |  Page : 270--272

Simultaneous occurrence of toxic epidermal necrolysis and neuroleptic malignant syndrome


Department of Dermatology and Venereology, Government Medical College, Kozhikode, Kerala, India

Correspondence Address:
K Muhammed
Kunnummal house, Koroth School Road, Vatakara-1, 673101, Kozhikode, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.16621

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Toxic epidermal necrolysis (TEN) is an acute life-threatening blistering disease characterized by involvement of the skin, multiple mucous membranes and internal organs. It is most commonly precipitated by the administration of medications like anticonvulsants. Neuroleptic malignant syndrome (NMS) is a rare complication of neuroleptic therapy characterized by catatonic behavior, generalized muscular rigidity, hyperthermia and autonomic dysfunction. An 18-year-old girl presenting with simultaneous appearance of TEN and NMS following anti-psychotic drugs given for bipolar mood disorder, is reported for the rare association and her complete recovery.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow