Indexed with PubMed and Science Citation Index (E) 
Users online: 3363 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
    Next article
    Previous article
    Table of Contents

    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded275    
    Comments [Add]    
    Cited by others 11    

Recommend this journal


Year : 2005  |  Volume : 71  |  Issue : 4  |  Page : 250--253

Post-kala-azar dermal leishmaniasis: A histopathological study

1 Departments of Dermatology, Venereology, All India Institute of Medical Sciences, New Delhi, India
2 Departments of Pathology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Sanjay K Rathi
Dr. Rathi's Skin Clinic, 143, Hill Cart Road, Siliguri - 734401, W. Bengal
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.16616

Rights and Permissions

BACKGROUND : Post-kala-azar dermal leishmaniasis follows an attack of visceral leishmaniasis and is caused by the same organism, i.e. Leishmania donovani. METHODS: In the present study, biopsy specimens from hypopigmented macules, nodules or plaques of 25 patients clinically diagnosed as PKDL were evaluated for epidermal and dermal changes and for the presence or absence of Leishmania donovani bodies (LDBs). RESULTS : The hypopigmented macules showed a patchy perivascular and periappendageal infiltrate with no demonstrable LDBs in any of the biopsies. In the nodular and plaque lesions, the infiltrate was diffuse, beneath an atrophic epidermis (74%) and follicular plugging (95.6%) was seen in most biopsies. The infiltrate consisted of lymphocytes, histiocytes and plasma cells in decreasing order of presence. LDBs could be demonstrated in only 10 (43.5%) biopsy specimens from nodular and plaque lesions and were never numerous. CONCLUSIONS: Histopathological features of PKDL are elucidated and discussed.


Print this article     Email this article

Online since 15th March '04
Published by Wolters Kluwer - Medknow