IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 3651 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  NAVIGATE Here 
    Next article
    Previous article
    Table of Contents

 RESOURCE Links
    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed12074    
    Printed212    
    Emailed14    
    PDF Downloaded391    
    Comments [Add]    
    Cited by others 18    

Recommend this journal

 

 STUDIES
Year : 2005  |  Volume : 71  |  Issue : 4  |  Page : 246--249

Correlation of the severity of atopic dermatitis with absolute eosinophil counts in peripheral blood and serum IgE levels


1 Departments of Dermatology, Institute of Child Health, Kolkata, India
2 Departments of Pediatrics, Institute of Child Health, Kolkata, India
3 Department of Pathology, AMRI-Apollo Hospitals, Kolkata, India

Correspondence Address:
Sandipan Dhar
Flat 2A2, Block 2, 5, N.S.C. Bose Road, Kolkata - 700 040
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0378-6323.16615

Rights and Permissions

BACKGROUND: Although a number of epidemiological studies, showing incidence and prevalence of atopic dermatitis, were available, scant attention has been paid to the correlation between the parameters of the disease like severity, absolute eosinophil count and IgE level, which has been known to be associated inconsistently. Hence this study was undertaken. METHODS: A total of 102 patients of atopic dermatitis, both children and adults, and 107 age matched controls were studied at the Pediatric Dermatology clinic, Institute of Child Health and department of Dermatology, AMRI-Apollo hospitals, Kolkata. RESULTS: The average age of onset of atopic dermatitis was observed to be 4.55 years. Both the average absolute eosinophil count and IgE levels in patients of atopic dermatitis were significantly higher than that of the controls. Each of these parameters showed significant correlation with severity of the disease and showed a nonhomogeneous distribution reflected by significant association with personal history of bronchial asthma and family history of atopy, when both parents were atopic. CONCLUSIONS: Our study shows that clinical activity of the disease as recorded by the "SCORAD" index can be used as an indicator of the hematological abnormalities as well as to some extent as a prognostic indicator. Family history of atopy correlates with the hematological abnormalities only if both parents are involved and bronchial asthma is the only associated atopic condition which correlates with the parameters of the disease .






[FULL TEXT] [PDF]*


        
Print this article     Email this article

Online since 15th March '04
Published by Wolters Kluwer - Medknow