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Year : 2005  |  Volume : 71  |  Issue : 3  |  Page : 199--201

Chronic granulomatous disease

Department of Dermatology and Venereology, Medical College Hospital, Trivandrum - 695 011, Kerala, India

Correspondence Address:
Pradeep S Nair
Kamala Sadan, Thampuran Mukku, Kunnukuzhy, Trivandrum - 695 037, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.16240

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A 2-year-old child presented with multiple discrete granulomatous lesions on the face and flexural regions since the age of 2 months along with lymphadenopathy. The patient also had recurrent bouts of pyodermas and respiratory tract infections. Biopsy of the lesion showed necrosis of tissue with suppuration and histiocytes but no evidence of tuberculosis, fungal infections or atypical mycobacteria. Lymph node biopsy also showed necrosis with suppuration but no infective organism. Nitroblue tetrazolium test was negative indicating that the neutrophils failed to oxidize the dye. We are reporting here a rare case of chronic granulomatous disease.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow