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Year : 2005  |  Volume : 71  |  Issue : 3  |  Page : 197--198

Malignant acanthosis nigricans with liver secondaries from an occult primary adenocarcinoma of gastrointestinal tract

Department of Dermatology and Venereology, Medical College Hospital, Trivandrum - 695 011, Kerala, India

Correspondence Address:
Pradeep S Nair
Kamala Sadan, Thampuran Mukku, Kunnukuzhy, Trivandrum - 695 037, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.16239

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A 38-year-old female presented with hyperpigmented velvety plaques on the nape and the sides of the neck with diffuse pigmentation of the face and flexures suggestive of acanthosis nigricans. The dorsa of both the hands showed increased rugosity, hyperpigmentation and hyperkeratosis of the palms, suggestive of tripe palms. Investigations revealed multiple secondaries in the liver. Histopathology showed the secondaries to be from adenocarcinoma of the gastrointestinal tract.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow