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Year : 2005  |  Volume : 71  |  Issue : 1  |  Page : 41--43

Pigmented xerodermoid - Report of three cases

Department of Dermatology, Vivekananda Institute of Medical Sciences and Ramakrishna Mission Seva Pratisthan Hospital and 99, Sarat Bose Road, Kolkata - 700 026, India

Correspondence Address:
Jayanta Kumar Das
Flat BE 3, 193 Andul Road, Howrah - 711109, W.B
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0378-6323.13786

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Pigmented xerodermoid, a rare genodermatosis, presents with clinical features and pathology similar to xeroderma pigmentosum, but at a later age. DNA repair replication is normal, but there is total depression of DNA synthesis after exposure to UV radiation. Two siblings in their teens and a man in his thirties with features of pigmented xerodermoid, e.g. photophobia, freckle-like lesions, keratoses, dryness of skin, and hypo- and hyper-pigmentation, are described. Although classically the onset of pigmented xerodermoid is said to be delayed till third to fourth decade of life, it seems the disease may appear earlier in the tropics. Early diagnosis and management could be life-saving.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow