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 CASE REPORT
Year : 2004  |  Volume : 70  |  Issue : 6  |  Page : 357--360

Bipolar aphthosis presenting as mutilating genital ulcers in women


1 Department of Dermatology, Venereology and Leprology, PGIMER, Chandigarh, India
2 Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India

Correspondence Address:
Bhushan Kumar
Dept. of Dermatology, Venereology and Leprology, PGIMER, Chandigarh - 12
India
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Source of Support: None, Conflict of Interest: None


PMID: 17642663

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Three women with large, mutilating genital ulcers of long duration, destroying almost the lower half of the external genitalia, are reported. They had a history of recurrent oral ulcers as well. All patients had been diagnosed as having 'genital ulcer syndrome' in the past and had been treated with antimicrobials. Histopathology of the biopsy from the margin of the ulcer revealed features of leukocytoclastic vasculitis. Considering the history, clinical features and histology, a diagnosis of bipolar aphthosis was made in all patients. All patients responded well to immunosuppressive therapy. The cases are reported because of the presence of genital ulcers of an unusually large size, mutilating character and their close similarity to genital ulcers due to sexually transmitted diseases, especially genital herpes and donovanosis.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow