IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 1385 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  NAVIGATE Here 
    Next article
    Previous article
    Table of Contents

 RESOURCE Links
    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed6417    
    Printed148    
    Emailed2    
    PDF Downloaded186    
    Comments [Add]    
    Cited by others 5    

Recommend this journal

 

 CASE REPORT
Year : 2004  |  Volume : 70  |  Issue : 4  |  Page : 234--235

Lichen planus secondary to hepatitis B vaccination


Department of Skin and STD, Kasturba Medical College, Manipal, India

Correspondence Address:
Shrutakirti D Shenoi
Dept of Skin and STD, Kasturba Medical College, Manipal
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 17642622

Rights and PermissionsRights and Permissions

The association of lichen planus (LP) with liver diseases is now well established. Recent reports suggest that the hepatitis viruses may play a central role in this association. Lichen planus following hepatitis B vaccination is much more unusual. A 19-year-old previously healthy male developed itchy violaceous papules and plaques over the upper extremities eight to ten days after the first injection of hepatitis B vaccine. He developed similar lesions over the upper trunk, neck and lower leg after the second and third injections. A skin biopsy showed a lichenoid tissue reaction. Direct immunofluorescence (DIF) showed multiple colloid bodies and a strong continuous ragged basement membrane zone (BMZ) band with fibrinogen. HbsAg by ELISA and anti-HCV antibodies were negative. The patient was treated with oral steroids and the lesions improved. LP is a pruritic inflammatory dermatosis of unknown origin. An increased prevalence of liver disease in patient with LP has been reported. Since the first case reported by Rebora in 1990, about 15 cases of LP occurring after hepatitis B vaccination have been reported in the literature irrespective of the type of vaccine used.






[FULL TEXT] [PDF]*


        
Print this article     Email this article

Online since 15th March '04
Published by Wolters Kluwer - Medknow