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 STUDIES
Year : 2004  |  Volume : 70  |  Issue : 1  |  Page : 25--28

Multicenter, open-label, non-comparative study of a combination of polytar and zinc pyrithione shampoo in the management of dandruff


1 Department of Skin & STD, Grant Medical College, Mumbai, India
2 Consultant Pharmacologist, Mumbai, India

Correspondence Address:
Shailendra N Sawleshwarkar
Department of Skin & STD, Grant Medical College, Byculla, Mumbai - 400008
India
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Source of Support: None, Conflict of Interest: None


PMID: 17642553

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Background: Dandruff is a common condition in clinical practice. We undertook a study to evaluate the efficacy and safety of a combination of zinc pyrithione and polytar in a shampoo base for the treatment of dandruff. Methods: A combination of polytar (1%) and zinc pyrithione (1%) was used for 4 weeks to treat 954 patients suffering from mild to severe dandruff. Scoring of dandruff was done on a 0-10 scale for each of the 6 regions of scalp at weeks 0, 2, 4 and 6. Follow up was for 2 weeks. Results: There was consistent improvement in dandruff scores over the treatment and the follow up period. There was significant improvement in signs and symptoms such as erythema and itching, with a negligible adverse event profile. The global assessment by investigators showed good-excellent results in the majority of patients and there was high acceptability for the treatment among the patients. Conclusion: A combination shampoo of polytar (1%) and zinc pyrithione (1%) offers a safe and effective option in the treatment of dandruff and its associated symptoms.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow