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 ORIGINAL ARTICLE
Year : 2003  |  Volume : 69  |  Issue : 4  |  Page : 271--273

Topical lincomycin gel in acne vulgaris: A multicentric placebo controlled study


1 Wallace Pharmaceutical Ltd., Mumbai, India
2 Department of Skin & VD, KEM Hospital, Mumbai, India
3 Department of Dermatology, Govt. General Hospital, Chennai, India
4 Department of Dermatology, Govt. General Hospital, Chennai, India
5 Department of Skin & VD, Medical College, Goa, India
6 Department of Dermatology, B. J. Medical College & Civil Hospital, Ahmedabad, India
7 Govt. Medical College & Associated Hospitals, Jammu, India

Correspondence Address:
A D Sharma
Wallace Pharmaceutical Pvt. Ltd., A-101/102, Floral Deck Plaza, Off Central MIDC Road, Andheri (E), Mumbai - 400073
India
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Source of Support: None, Conflict of Interest: None


PMID: 17642909

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Introduction: Acne vulgaris is commonly treated with topical antibacterials. We evaluated lincomycin gel, a new topical formulation for mild to moderate acne. Material and Methods: A multicentric, randomized, double blind, placebo controlled, clinical trial was conducted with lincomycin hydrochloride in 2% gel form in 200 patients with grade II and grade III acne. The severity of acne lesions was noted at baseline and after 4 weeks. Results: About 70% cases in the study group showed a good to excellent response, which was significantly more as compared to 23% in the placebo group. The frequency and severity of adverse reactions in the two groups were similar. Conclusion: Lincomycin hydrochloride gel is an effective and safe treatment option for mild to moderate acne vulgaris.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow