| SHORT COMMUNICATION
|Year : 2002 | Volume
| Issue : 4 | Page : 225--226
Sezary syndrome - Without erythroderma
K Abdul Samad, K Prasanna Moorthy, P Akhar Ali
Department of Dermatology and Venereology Medical College, Trivandrum, Kerala, India
Sezary syndrome (SS), is described as the classical triad of pruritic erythroderma, lymphadenopathy, and presence of more than 10% of circulating Sezary cells in the peripheral blood. We report on unusual case of advanced cutaneous T - cell lymphoma with classical haematological and histopathological features of Sezary syndrome, but lacking the clinical features of erythroderma.
A 66 year old man presented with asymptomatic multiple papules, plaques and nodules and with generalized lymphadenopathy. Peripheral smear showed more than 60% of Sezary cells. Skin and lymph node biopsy showed typical features of T-cell lymphoma and immunohistochemistry and CD marker studies showed the cells to be atypical T-lymphocytes. This unusual case is highlighted to denote that erythroderma need not be taken as a hard and fast criterion for diagnosing Sezary syndrome.
K Abdul Samad
Department of Dermatology and Venereology Medical College, Trivandrum, Kerala
Source of Support: None, Conflict of Interest: None
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