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Year : 2001  |  Volume : 67  |  Issue : 3  |  Page : 124--125

Role of oral vitamin D3 analogues in the treatment of psoriasis

Department of Dermatology, Dayanand Medical College & Hospital, Ludhiana, India

Correspondence Address:
Alka Dogra
Department of Dermatology, Dayanand Medical College & Hospital, Ludhiana
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Source of Support: None, Conflict of Interest: None

PMID: 28615563

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Oral vitamin D3 analogues 1 alpha hydroxy cholecalciferol and 1,25 dihydroxy cholecalciferol were compared with placebo in the treatment of psoriasis. Three groups of 15 patients each were given 1 α hydroxy cholecalciferol at 1 ug/ day 1,25 dihydroxy cholecalciferol at 0.5 ug/d and multi vitamins other than Vit A and Vit D, respectively. Patients were followed up for 3-6 months. Assessment of severity and response was done by Psoriasis Area Severity Index (PASI). Both Vit D, analogues 1 α hydroxy vitamins D3 and 1,25 (OH)2 D3 were found to be effective. Serum and urinary calcium remained within normal limits.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow