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 COSMETOLOGY
Year : 2001  |  Volume : 67  |  Issue : 2  |  Page : 82--84

Chemical peeling - Glycolic acid versus trichloroacetic acid in melasma


Department of Dermatology, Venereology & Leprology. SN Medical College, Jodhpur, India

Correspondence Address:
G Kalla
4F-12 "Sugyajan', New power House Road, Jodhpur (Rajasthan) -342 003
India
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Source of Support: None, Conflict of Interest: None


PMID: 17664715

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Melasma continues to be a therapeutic challenge. 100 patients of melasma not responding to conventional depigmenting agents were divided into 2 groups, one treated with 55 - 75% glycolic acid (68 patients) and the other with 10-15% trichloroacetic acid (32 patients). Applications were made after every 15 days and response assessed clinically along with relapse or hyperpigmentation after 3 month follow up period. More than 75% improvement was seen in 30%, and 50-75% improvement in 24% patients. Response with TCA was more rapid as compared to GA. Chronic pigmentation responded more favourably to TCA. Relapse and hyperpigmentation was more-25% in TCA as compared to 5.9% GA. Sun exposure was the most important precipitating factor followed by pregnancy and drugs.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow