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 ORIGINAL ARTICLE
Year : 2001  |  Volume : 67  |  Issue : 2  |  Page : 69--71

A study of dapsone syndrome at a rural teaching hospital in South India


Department of Dermatology, Rajah Muthiah Medical College & Hospital, Annamalai Vniversity,Annamalainagar-608002, India

Correspondence Address:
P VS Prasad
88, Auta Nagar, Sivapuri Post, Annamalainagar-608002,Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


PMID: 17664711

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Dapsone syndrome or sulphone syndrome was noticed within four to six weeks of starting treatment in 10 out of 604 patients (1.6%) on MDT for leprosy treated at Rajah Muthiah Medical College Hospital,South Arcot District, Tamil Nadu State during the period 1995-1998.Patients developed either maculo papular rash or exfoliation along with fever and lymphadenopathy.Abonormal liver function tests were noticed in 50%.The patients with dapsone syndrome were treated with corticosteriods after withdrawing dapsone.There was complete resolution of skin lesions and other symptoms.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow