|LETTER TO EDITOR
|Year : 2000 | Volume
| Issue : 3 | Page : 161
Therapy For an Extensive Childhood Vitiligo (le)
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Ghrarami R. Therapy For an Extensive Childhood Vitiligo (le). Indian J Dermatol Venereol Leprol 2000;66:161
To the Editor
Vitiligo, a common disorder of pigmentation is still compelling the Dermatologists to feel uncomforTable regarding its treatment. Among the various modes of therapy, topical steroids and topical PUVA are impracticable for generalised vitiligo and oral PUVA is contraindicated in childhood vitiligo. In this situation, systemic steroid, once daily for a long time may help but it is having unaccepTable side effects.' To counteract this, pulse steroid has been launched during last few years.
A 5-year-old girl presented with extensive vitiligo of 6 months duration. The lesions were more than 100 in number, size-varied from i to 2 cm in diameter and distributed over face, trunk and limbs; but sparing scalp, palms, soles, and mucosal surfaces. Routine examination of blood, urine, stool, LFT, chest X-ray, blood sugar, sodium, potassium and chloride were normal.
Patient was given 2.5 mg of betamethasone sodium phosphate orally for 2 consecutive days per week along with antacid and potassium chloride supplementation. She was followed up at 4 weekly interval and at every visit her weight, blood sugar, blood pressure were checked.
Pigmentation started from the end of first month of therapy which was assessed by photography. Complete repigmentation occurred following one year of treatment without any side effects and steroid was gradually tapered and stopped within another 3 months. There was no relapse of the disease while on follow up for 6 months
| References|| |
|1.||Kim SM, Lee HS, Hann SK. The efficacy of low-dose oral corticosteroids in the treatment of vitiligo patients. Int 3 Dermatol 1999;38:546-550. |
|2.||Pasricha JS, Khaitan BK. Oral mini-pulse therapy with betamethasone in vitiligo patients having extensive or spreading disease. Indian J Dermatol 1993; 32: 753-757. [PUBMED] |
|3.||Seiter 5, Ugurel S, Pfohler C, et al. Successful treatment of progressive vitiligo with high-dose intravenous methylprednisolone,'pulse'threrapy. Dermatology 1999; 199:261-262. |