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Year : 2000  |  Volume : 66  |  Issue : 3  |  Page : 161

Therapy For an Extensive Childhood Vitiligo (le)

Correspondence Address:
Ramesh Ghrarami

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Source of Support: None, Conflict of Interest: None

PMID: 20877066

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How to cite this article:
Ghrarami R. Therapy For an Extensive Childhood Vitiligo (le). Indian J Dermatol Venereol Leprol 2000;66:161

How to cite this URL:
Ghrarami R. Therapy For an Extensive Childhood Vitiligo (le). Indian J Dermatol Venereol Leprol [serial online] 2000 [cited 2020 Mar 29];66:161. Available from: http://www.ijdvl.com/text.asp?2000/66/3/161/4909

To the Editor

Vitiligo, a common disorder of pigmentation is still compelling the Dermatologists to feel uncom­forTable regarding its treatment. Among the vari­ous modes of therapy, topical steroids and topical PUVA are impracticable for generalised vitiligo and oral PUVA is contraindicated in childhood vitiligo. In this situation, systemic steroid, once daily for a long time may help but it is having unaccepTable side effects[1].' To counteract this, pulse steroid has been launched during last few years.[2][3]

A 5-year-old girl presented with extensive viti­ligo of 6 months duration. The lesions were more than 100 in number, size-varied from i to 2 cm in diameter and distributed over face, trunk and limbs; but sparing scalp, palms, soles, and mucosal sur­faces. Routine examination of blood, urine, stool, LFT, chest X-ray, blood sugar, sodium, potassium and chloride were normal.

Patient was given 2.5 mg of betamethasone sodium phosphate orally for 2 consecutive days per week along with antacid and potassium chloride supplementation. She was followed up at 4 weekly interval and at every visit her weight, blood sugar, blood pressure were checked.

Pigmentation started from the end of first month of therapy which was assessed by photogra­phy. Complete repigmentation occurred following one year of treatment without any side effects and steroid was gradually tapered and stopped within another 3 months. There was no relapse of the dis­ease while on follow up for 6 months

  References Top

1.Kim SM, Lee HS, Hann SK. The efficacy of low-dose oral corti­costeroids in the treatment of vitiligo patients. Int 3 Dermatol 1999;38:546-550.  Back to cited text no. 1    
2.Pasricha JS, Khaitan BK. Oral mini-pulse therapy with betamethasone in vitiligo patients having extensive or spreading disease. Indian J Dermatol 1993; 32: 753-757.  Back to cited text no. 2  [PUBMED]  
3.Seiter 5, Ugurel S, Pfohler C, et al. Successful treatment of progressive vitiligo with high-dose intravenous methylpredniso­lone,'pulse'threrapy. Dermatology 1999; 199:261-262.  Back to cited text no. 3    


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