|Year : 2000 | Volume
| Issue : 2 | Page : 89-90
Naevus depiomentosus treated with suction blister grafting
BC Ravikumar, L Sabitha, C Balachandran
B C Ravikumar
Source of Support: None, Conflict of Interest: None
Naevus depigmentosus is a congenital hypomelanotic condition in which the off white lesions are permanent and cosmetically embarassing. There has been no effective treatment reported so for for this condition. Here we are reporting a patient of naevus depigmentosus on whom we performed suction blister grafting and the resultant pigmentation was satisfactory
Keywords: Naevus depigmentosus, Blister grafting
|How to cite this article:|
Ravikumar B C, Sabitha L, Balachandran C. Naevus depiomentosus treated with suction blister grafting. Indian J Dermatol Venereol Leprol 2000;66:89-90
|How to cite this URL:|
Ravikumar B C, Sabitha L, Balachandran C. Naevus depiomentosus treated with suction blister grafting. Indian J Dermatol Venereol Leprol [serial online] 2000 [cited 2019 Sep 20];66:89-90. Available from: http://www.ijdvl.com/text.asp?2000/66/2/89/4879
| Introduction|| |
Naevus depigmentosus (ND) is an uncommon, congenital, stable hypo-melanosis first described by Lesser in 1884.  The lesions usually present as quasidermatomal macules commonly on the trunk, lower abdomen or proximal extremities. They are off-white in colour and have irregular, serrated, feathered or geographic margins. Unfortunately there is no effective treatment for this condition. Here we are reporting a patient of ND treated successfully with suction blister grafting.
| Case Report|| |
A 19-year-old female student presented with a hypopigmented asymptomatic macule on the left anterolateral aspect of the neck since birth. The lesion was measuring 3X4 cm. On pressing the lesional border, there was no disappearance of the hypopigmentation. Examination of other areas of the skin did not reveal any similar lesions or any other type of skin lesions and the other systems particularly the skeletal and nervous system were within normal limits.
Her investigation revealed normal blood picture, LFT, RFT and the clotting profile and the test for HIV was negative.
After taking the consent, suction blister graft ing was performed on her. Two blisters of about 3 cms diameter were raised on the left thigh using a suction machine with a cup applying 250 mm Hg pressure for about 2 hours. Phototherapy was given to the recipient ND area after applying melanocyl 0.75% lotion with 15 J/sqms of UVA on three occasions 30 hrs, 24 hours and 6 hours before doing the procedure. During phototherapy, the surrounding normal skin was protected with sunscreens. In the next step, the recipient area where phototoxic blister had formed was gently dermabraded with a gauze piece. Then the blister roof from the thigh was removed with the help of iris scissors, transferred on to a glass slide and the edges were trimmed to fit the recipient area shape and then applied on to the recipient ND site [Figure - 1]. When the dressing was removed after 48 hours, the graft was well taken. The resultant pigmentation was satisfactory after 1 month of follow up [Figure - 2].
| Discussion|| |
Naevus depigmentosus is a congenital pigmentary disorder without causing any physical distress to the patient. Though there are occassional reports of neurological abnormalities  and limb hypertrophy  associated with naevus depigmentosus, the disease is primarily limited to the skin. Though, the disease to this extent is very innocuous, the resultant cosmetic discomfort especially when the lesions are present on the face and neck can be embarassing to the patient. Therefore for a condition like ND which is just a cosmetic blemish and for which, hitherto no effective therapies were available, blister grafting is very effective and should be considered in all willing patients.
| References|| |
|1.||Mosherr DB, Fitzpatrick TB, Hory Y, et al. Disorders of melanocyte In: Dermatology in General Medicine, Fitzpatrick TB, et al (Eds), Newyork, McGraw-Hill, 1993, 4th edition, pp-9444-945. |
|2.||Farciso A, Alvarez G. Naevus acromico unilaterral en bandas en oligofrence. Rev Assoc Med Argent 1938; 52:158. |
|3.||Fitzpatrick TB. In: discussion, Berg M, Tarnowski W; Naevus depig mentosus. Arch Dermatol 1974; 109: 920. |
[Figure - 1], [Figure - 2]