IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 2778 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   [PDF Not available] *
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
   References

 Article Access Statistics
    Viewed2781    
    Printed40    
    Emailed1    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal

 


 
LETTER TO EDITOR
Year : 2000  |  Volume : 66  |  Issue : 2  |  Page : 107

Dexamethasone pulse for generalized lichen planus



Correspondence Address:
J S Pasricha


Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 20877047

Rights and PermissionsRights and Permissions



How to cite this article:
Pasricha J S. Dexamethasone pulse for generalized lichen planus. Indian J Dermatol Venereol Leprol 2000;66:107

How to cite this URL:
Pasricha J S. Dexamethasone pulse for generalized lichen planus. Indian J Dermatol Venereol Leprol [serial online] 2000 [cited 2019 Jun 24];66:107. Available from: http://www.ijdvl.com/text.asp?2000/66/2/107/4889


To the Editor

The article published in the Indian J Dermatol Venereol Leprol 1998;64:103 by Mittal et al was interesting. I wish to inform your readers that we have used dexamethasone pulse therapy for several serious and/or generalized skin diseases including lichen planus. This has been mentioned in our recent publication, Pulse Therapy in Pemphigus and Other Diseases, 1998 edited by me. We however use 100 mg dexamethasone for 3 consecutive days, and repeat such pulses at 28-day intervals. The results are excellent. Interestingly, in spite of the very high dose of dexamethasone there are no side effects attributable to the corticosteroid.

Several patients however, especially those who are afraid of the pricks, prefer to take oral treatment. The oral treatment for lichen planus should consist of 2.0mg betamethasone taken as a single oral dose with the morning breakfast daily for 1 month, by which time all the lichen planus lesions regress completely. Thereafter, the dose is to be reduced by 0.5mg per month.[1] The total treatment lasts 4 month. The relapse rate after this course is negligible (less than10%) and the side effects expe­rienced during this period are by and large reversible. Any regimen less than that increases the chance of a relapse.



 
  References Top

1.Pasricha J S. Lichen planus.In: Treatment of Skin Diseases. 4th Ed Oxford and IBH, New Delhi, 1991;190-193.  Back to cited text no. 1    




 

Top
Print this article  Email this article
Previous article Next article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow