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Year : 2000  |  Volume : 66  |  Issue : 2  |  Page : 104-105

Bilateral nevus of ota

Correspondence Address:
Kumar Asok Gangopadhyay

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Source of Support: None, Conflict of Interest: None

PMID: 20877045

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Nevus of Ota affecting bilaterally on the face is being reported in two women

How to cite this article:
Gangopadhyay KA. Bilateral nevus of ota. Indian J Dermatol Venereol Leprol 2000;66:104-5

How to cite this URL:
Gangopadhyay KA. Bilateral nevus of ota. Indian J Dermatol Venereol Leprol [serial online] 2000 [cited 2020 May 25];66:104-5. Available from: http://www.ijdvl.com/text.asp?2000/66/2/104/4887

  Introduction Top

Nevus of OTA is a macular or slightly raised pigmented spot on the face in the distribution of ophthalmic, maxillary or rarely mandibular distribution of trigeminal nerve, along with ipsilateral hyperpigmentation of the various structures of the eye. The women are more frequently affected than men and it is very rare to occur in bilateral distribution. [1] The author reported an unique case of bilateral nevus of OTA, in a male pateint earlier. [2] Two interesting cases of bilateral nevus of OTA both in female patients are being reported here.

  Case Report Top

[TAG:2]Case 1.[/TAG:2].

A young woman of 25, presented with hyperpigmented macular lesions on both sides of the cheek since her infancy. The pigmentation appeared over both the cheeks simultaneously and they enlarged very incidiously to the present size in a course of 15 years. The hyperpigmentation of the sclera of both the eyes were noticed one year after the appearance of the cutaneous pigmentation. Apart from the cosmetic problem the patient had no symptom as such. Examination revealed scattered bluish grey macules over both the cheeks. There were mot­tied bluish hyperpigmentation over the inferior and lateral aspect of the sclera of both the eyes. The palpebral conjunctiva, iris and cornea were free of any lesion, nor there was any pigmentation in oral mucosa. There was no significant personal and fam­ily history.

[TAG:2]Case 2.[/TAG:2]

A 30- year- old woman presented with the complaint of hyperpigmentation of both the cheeks extending up to the lateral aspect of the forehead which was there since her birth [Figure - 1]. The lesion appeared as insignificant bluish macules on both cheeks which gradually increased in size very slowly and ultimately spread to the lateral aspects of forhead. Interestingly she had bluish pigmentation over superio- lateral aspect of the sclera of the right eye which appeared in her infancy.The left eye was absolutely free of any lesion. There was no significant personal or family history.

Histologically in both the cases epidermis was unremarkable. Numerous dendritic melanocytes were scattered along the collagen bundles throughout the dermis [Figure - 2].

  Discussion Top

This syndrome was first described by OTA as 'Nevus fusco - caeruleus - opthalmo - maxillaris' in 1939. [3] Nevus of OTA is not a hereditary disease, although it has been reported in close relatives. It is prevalent among the Japanese, not uncommon in Orientals, but rare in Indians. [2] It is mostly unilateral and bilateral involvement is seen only in 5% cases. About 80% of the patients with this nevus are females. It is cogenital in 50% cases, the rest ap­pearing in the first decade of life.

The two cases reported herein are interesting because nevus of OTA is very rare in bilateral distribution. While the first patient had the onset at her infancy, in the second patient - her eye involvement was unilateral.

  References Top

1.Sharma RP, Sarma NK, Jain V, et al. Bilateral nevus of OTA, Indian J Dermatol Venereol Leprol 1994:60:235.  Back to cited text no. 1    
2.Gangapadhyay AK. Indian J Dermatol Venereol Leprol 1997; 63: 50-52.  Back to cited text no. 2    
3.Panja SK, Banerjee BN. Navus fuscocaeruleus ophthalmo maxillaris. Indian 3 Dermatol 1968 ; 14 : 9 - 11.  Back to cited text no. 3    


[Figure - 1], [Figure - 2]


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