|Year : 2000 | Volume
| Issue : 1 | Page : 43-44
Cutaneous sarcoidosis without systemic involvement
Gurcharan Singh, Prabhakar Sangolli, K Dash, Grove
Source of Support: None, Conflict of Interest: None
A 49-year -old woman presenting with features of cutaneous sarcoidosis without any evidence of systemic involvement is reported.
Keywords: Cutaneous sarcoidosis
|How to cite this article:|
Singh G, Sangolli P, Dash K, Grove. Cutaneous sarcoidosis without systemic involvement. Indian J Dermatol Venereol Leprol 2000;66:43-4
|How to cite this URL:|
Singh G, Sangolli P, Dash K, Grove. Cutaneous sarcoidosis without systemic involvement. Indian J Dermatol Venereol Leprol [serial online] 2000 [cited 2019 Oct 16];66:43-4. Available from: http://www.ijdvl.com/text.asp?2000/66/1/43/4865
| Introduction|| |
Sarcoidosis is a systemic disease of unknown etiology. The diagnosis is based on the consistent clinical, biological and radiological findings, supported by histological evidence of noncaseating epitheloid granuloma. Skin lesions occur in about a quarter of patients with sarcoidosis. Cutaneous sarcoidosis is invariably associated with some form of systemic component and sarcoidosis confined to skin only is very rare. 
| Case Report|| |
A 49-year old lady presented with asymptomatic eruption over the face, limbs, and trunk of 1.5 years duration. Patient denied preceding history of insect bite or trauma and there was no history of fever, cough, weight loss, joint pains, eye complaints or any other systemic complaints. Past and family history were not contributory.
General physical and systemic examination were normal.
Dermatological examination revealed asymmetrically distributed erythematous nodules and plaques with slight scaling measuring about 2-3cms., near inner canthus of left eye both forearms,trunk, thighs, and around knee joints. Lesions were nontender and mobile. Palms, soles, hairnail and mucosae were uninvolved.Opthalmological examination was normal.
Investigations revealed raised globulins (4.1gm/dI) and SACE (55U/dI) levies, negative Mantoux test, with normal LFT, serum and 24 hrs urinary calcium, serum creatinine and blood urea. Radiological examination of chest, hands and feet, ultrasound abdomen and lung function tests revealed no abnormality.
Skin biopsy revealed epitheloid granulomas with Langhans giant cells, thin zone of lymphocytes and intact reticulum fibers in upper and mid dermis.
Special stains for AFB, LD bodies and calcium were negative. Lesions subsided with chloroquin therapy. There has been no fresh skin lesions and patient has not developed manifestations of sarcoidosis during the follow up for a period of 2 years so far.
| Discussion|| |
Skin sarcoidosis is morphologically classified into three basic groups. Erythema nodosum, scar sarcoidosis and skin sarcoid. Skin sarcoid is characterised by specific cutaneous lesions of sarcoidosis and may take nodular, plaque angiolupoid, subcutaneous and some other forms. Clinical manifestations of skin sarcoid are usually asymptomatic and polymorphous.
Cutaneous sarcoidosis has been reported rarely from India and in all these reports, lesions of skin were associated with some forms of systemic involvement.,,Therefore patients presenting with disease confined to skin alone, should be followed up regularly for the probable risk of developing systemic manifestations at a later date.
| References|| |
|1.||Hubert A, Wattesuw G, Tannouri F, et al. Systemic sarcoidosis with cutaneous lesions: Literature review. Acta Clin Belg 1995; 50: 207-213. |
|2.||Singh SK, Singh S, Pandey SS. Cutaneous sarcoidosis without systemic involvement: Response to intralesional corticosteroid. Indian J Dermatol Venereol Leprol 1996; 62: 273-374. |
|3.||Suga Y, Owava H. Sarcoidosis of skin. Nippon Ruisho 1994; 52: 1603-1607. |
|4.||Ghorpade A, Ramanan C. Cutaneous sarcoidosis. Indian J Dermatol Venereol Leprol 1996;45:459-463. |
|5.||Bajaj AK, Lal M, Gupta SC, et al. Sarcoidosis: a case report. Indian J Dermatol Venereol Leprol 1979;45:459-462. |
|6.||Rajam RV, Vishwanathan GS, Rangaiah PN, et al. Sarcoidosis-a short review with a case report. Indian 3 Dermatol Venereol Leprol 1957;23:97-135. |