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Year : 1999  |  Volume : 65  |  Issue : 6  |  Page : 290-291

Giant molluscum contagiosum in an infant

Correspondence Address:
Prakash Kumar

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Source of Support: None, Conflict of Interest: None

PMID: 20921691

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How to cite this article:
Kumar P, Chatura K R, Jagannath V K, Hara. Giant molluscum contagiosum in an infant. Indian J Dermatol Venereol Leprol 1999;65:290-1

How to cite this URL:
Kumar P, Chatura K R, Jagannath V K, Hara. Giant molluscum contagiosum in an infant. Indian J Dermatol Venereol Leprol [serial online] 1999 [cited 2019 Nov 14];65:290-1. Available from: http://www.ijdvl.com/text.asp?1999/65/6/290/4844

  Introduction Top

Molluscum contagiosum is caused by a double stranded DNA virus of the family poxviridae. In children a typical head and neck distribution, with abundance of lesions is seen and is believed to spread through fomites or casual contact.[1] This is a case report of an atypical presentation of molluscum contagiosum.

  Case Report Top

A 3-month-old male baby was noticed to have swellings on the scalp, increasing in size, of 15 days duration. The mother was the informant. There were multiple pedunculated, hairless swellings, in the right parietotemporal region. They were freely mobile with no discharge or ulceration. Clinically a diagnosis of squamous papilloma was made and a wide excision performed [Figure - 1].

The histological examination of the tumours showed an acanthotic epidermis. Many epidermal cells contained large intracytoplasmic inclusion bodies (molluscum bodies). Histopathological study rendered the definite diagnosis which was missed clinically because of the age, site and size.

A retrospective investigaion for HIV in the infant, was requested and the result was negative.

  Discussion Top

Molluscum contagiosum a pox virus infection, most commonly occurs in children and adolescents, and lesions are localised on the face, arms, legs and anogenital region. The mode of transmission may be by fomites or casual contact, [1] or by sexual route.

Atypical presentations are being increasingly reported in HIV infected patients, i.e., lesions are often upto 2cms in diameter or at greater frequencies. It may occur in patients with atopic eczema and congenital immunodeficiency.[2]

The reported lesions mimic comedones, abscesses, furuncles and giant nodular lesions. Biopsy is often necessary to distinguish between molluscum lesions and their cutaneous simulants.[3] Giant molluscum contagiosum presenting as basal cell carcinoma in an AIDS patient has also been reported.[4]

Giant molluscum contagiosum developing on the face of an AIDS patient has also been reported.[5]

Giant molluscum lesion in our patient was mistaken for a squamous papilloma. Histological diagnosis was followed by investigation for HIV status. The infant was HIV seronegative. Molluscum in AIDS is often a marker of late stage disease and may lead to disfiguring cutaneous lesions.[6] This report highlights the atypical presentation of molluscum contagiosum by its size, location and in an HIV seronegative infant.


[Figure - 1]


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Online since 15th March '04
Published by Wolters Kluwer - Medknow