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LETTER TO EDITOR
Year : 1999  |  Volume : 65  |  Issue : 3  |  Page : 152

Peyronies disease, scleroderma and diabetes mellitus




Correspondence Address:
Gurcharan Singh


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Source of Support: None, Conflict of Interest: None


PMID: 20921643

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How to cite this article:
Singh G, Nagaraja, Prabhu S, Mohan M. Peyronies disease, scleroderma and diabetes mellitus. Indian J Dermatol Venereol Leprol 1999;65:152

How to cite this URL:
Singh G, Nagaraja, Prabhu S, Mohan M. Peyronies disease, scleroderma and diabetes mellitus. Indian J Dermatol Venereol Leprol [serial online] 1999 [cited 2019 Jun 25];65:152. Available from: http://www.ijdvl.com/text.asp?1999/65/3/152/4796



  To the Editor Top


A 55-year-old man, known case of diabetes mellitus with hypertension presented with features of scleroderma (scleroderma, Raynaud's phenomenon and difficulty in swallowing) of 3 months duration. He also complained of impotence and increased curvature of penis on erection for the past 2 months.

Skin biopsy findings were consistent with scleroderma, ANA was negative and ultrasonography revealed hyperechoeic area in the upper third of penis suggestive of Peyronies disease. Prevalence of diabetes mellitus is reported higher in patients with Peyronies disease[1] and association with systemic sclerosis has also been documented in recent literature. [2, 3] Etiology of Peyronies disease remains a mystery, and recent studies on HLA antigens and immunological features suggest the hypothesis of an autoimmune etiology for the disorders. [4, 5] Peyronies disease co-existing with scleroderma and diabetes mellitus in the present case corroborates autoimmune basis of the disease[5].

 
  References Top

1.Culha M, Alici B, Acar O, et al. The relationship between diabetes mellitus, impotence and veno occlusive dysfunction in Peyronies disease patients. Urol Int 1988;60:101-104.  Back to cited text no. 1    
2.Ordi J, Selva A, Fonollosa V, et al. Peyronies disease in systemic sclerosis. Ann Rheun Dis 1990;49:134-135.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Gualdieri L, Valentil G, Lupoli S, et al. Peyronies disease in systemic sclerosis. Report of two cases. J Rheumatol 1988;15:380-381.  Back to cited text no. 3    
4.Rompel R, Mueller - Eckhardt G, Shroeder - Printzen I, et al. HLA antigens in Peyronies disease. Uro Int 1994;52:34-37.  Back to cited text no. 4    
5.Schiavino D, Sasso F, Nucera E, et al. Immunological findings in Peyronies disease. Urology 1997;50:764-768.  Back to cited text no. 5  [PUBMED]  [FULLTEXT]




 

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