|LETTER TO EDITOR
|Year : 1998 | Volume
| Issue : 5 | Page : 252-253
Repigmentation of leukotrichia over vitiligo patches after punch grafting
Subrata Malakar, Sandipan Dhar
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Malakar S, Dhar S. Repigmentation of leukotrichia over vitiligo patches after punch grafting. Indian J Dermatol Venereol Leprol 1998;64:252-3
|How to cite this URL:|
Malakar S, Dhar S. Repigmentation of leukotrichia over vitiligo patches after punch grafting. Indian J Dermatol Venereol Leprol [serial online] 1998 [cited 2019 Jun 20];64:252-3. Available from: http://www.ijdvl.com/text.asp?1998/64/5/252/4717
| To the Editor|| |
Vitiligo patches are often associated with leukotrichia which usually remains as such even after complete repigmentation of the patches. While surgically treating vitiligo by punch grafting we incidentally observed repigmentation of leukotrichia in three patients. It was noticed between 10 to 16 weeks. The repigmentation started after 3 to 4 weeks of the perigraft pigment spread in all the three patients.
Vitiligo patches are often associated with leukotrichia which makes them relatively resistant to medical treatment. Even after successful repigmentation of a vitiligo patch with PUVA therapy, the leukotrichic hairs remain depigmented causing tremendous psychological trauma to the patient. Of late punch grafting (PG) has revolutionised the treatment of stable and resistant vitiligo. This surgical technique alone with PUVA has been found to repigment the vitiliginous skin quite effectively. [3, 4] However, the issue of repigmentation of leukotrichia after PG has not been adequately addressed in the literature. Only recently split thickness skin graft (STSG) has been found to repigment leukotrichia along with the repigmentation of vitiligo patch. [1, 5]
After PG, the repigmentation of vitiligo patches occurs by the migration of melanin from the grafted skin in vitiliginous patch. Melanin remains in the melanocyte reservoir at the basal cell layer or the follicles. Although melanin freely travels to the basal keratinocytes of the vitiliginous skin to the hair cortical cells the transfer is often found to be inadequate. As a result, in spite of complete repigmentation of vitiligo patches, often leukotrichia persists. The reason for the inadequate or incomplete melanin transfer is not known . Although the issue of repigmentation of vitiligo patch has been thoroughly discussed, the question of repigmentation of leukotrichia has not been adequately highlighted in the literature.
Once the successful repigmentation of leukotrichia occurs along with the vitiligo patch, the ultimate cosmetic outcome is unique. At present, we have taken up the study to probe further and evaluate the rate, degree and extent of repigmentation of leukotrichia after PG in patients with vitiligo.
We like to share our preliminary observation of repigmentation of leukotrichia over vitiligo patches after punch grafting.
| References|| |
|1.||Agarwal K, Agarwal A. Vitiligo: Surgical repigmentation of leukotrichia. Dermatol Surg 1995;21:711-715. |
|2.||Falabella R. Treatment of localised vitiligo by autologous minigrafting, Arch Dermatol 1988;124:1649-1655. [PUBMED] [FULLTEXT]|
|3.||Savant SS. Autologous miniature punch grafting in stable vitiligo, Indian J Dermatol Venereol Leprol 1992;58:310-314. |
|4.||Malakar S. Dermatosurgical approach in vitiligo, Indian J Dermatol Venereol Leprol 1995;40:172-177. |
|5.||Hann SK, Im S, Park Y K, et al. Repigmentation of leukotrichia by epidermal grafting and systemic psoralen plus UVA, Arch Dermatol 1992;128:998-999. |