IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 1751 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   [PDF Not available] *
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
   To the Editor

 Article Access Statistics
    Viewed1948    
    Printed27    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal

 


 
LETTER TO EDITOR
Year : 1998  |  Volume : 64  |  Issue : 4  |  Page : 206-207

Effect of parenteral vitamin D3 in skin diseases



Correspondence Address:
Nusrat Banka


Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 20921767

Rights and PermissionsRights and Permissions



How to cite this article:
Banka N. Effect of parenteral vitamin D3 in skin diseases. Indian J Dermatol Venereol Leprol 1998;64:206-7

How to cite this URL:
Banka N. Effect of parenteral vitamin D3 in skin diseases. Indian J Dermatol Venereol Leprol [serial online] 1998 [cited 2019 Jul 22];64:206-7. Available from: http://www.ijdvl.com/text.asp?1998/64/4/206/4697



  To the Editor Top


Taking the clue from the topical use of vitamin D3 derivatives in psoriasis and its efficacy, we in AIMS, B.G. Nagar, tried vitamin D3 parenterally in psoriasis. For the experimentation we used Arachitol of Duphor company, 3 lakhs international units intramuscularly every week for 4 weeks and we found substantial improvement in 4 patients. In first week itself, there was decrease of erythema and scaling. By the end of 4 weeks erythema disappeared, the plaque thickness diminished by 80%, no new lesions appeared and some lesions disappeared altogether. What is of interest is that all four patients had extensive psoriasis, involving around 40% of skin surface and not few plaques.

Extending this interesting observation further, we tried the same dose in 2 cases of lichen planus. After 2 weeks, the lesions regressed by 50%. Some lesions disappeared and new ones did not appear. Both the patients had complete relief from itching.

We tried the same regimen in 4 cases of photodermatitis. After 4 weeks the lesions in all disappeared leaving residual pigmentation. All had complete freedom from itching.

The conclusion therefore is that vitamin D3, parenterally has got antipruritic, anti-inflammatory and healing properties, on skin. It is also evident that vitamin D3 administered intramuscularly could be a good adjuvant to existing dermatological therapies.

The only theoretical objection for using vitamin D3, parenterally, could be hypercalcemia. However even after repeated checking in these patients serum clcium levels did not cross 11 mg%.

We are reporting this observation, because we feel that parenteral vitamin D3 may prove an important medicine or an adjuvant in the treatment of many skin conditions.






 

Top
Print this article  Email this article
Previous article Next article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow