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Year : 1998  |  Volume : 64  |  Issue : 3  |  Page : 157-158

Treatment of nodular scabies (le)

Correspondence Address:
R R Mittal

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Source of Support: None, Conflict of Interest: None

PMID: 20921751

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How to cite this article:
Mittal R R, Jain C, Jindal R. Treatment of nodular scabies (le). Indian J Dermatol Venereol Leprol 1998;64:157-8

How to cite this URL:
Mittal R R, Jain C, Jindal R. Treatment of nodular scabies (le). Indian J Dermatol Venereol Leprol [serial online] 1998 [cited 2020 May 31];64:157-8. Available from: http://www.ijdvl.com/text.asp?1998/64/3/157/4680

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Nodular scabies (NS) presents as pruritic, persistent nodules for weeks or months even after successful treatment of scabies. Scabicidal drugs include 5-10% sulfur, 25% benzyl benzoate, 1% gamma benzene hexachloride, 25% monosulfiram, 5% permethrin, 5- 10% thiabendazole and 10% crotamiton. Other modalities for treating nodules in scabies include intralesional steroids and surgical excision.[1] Crotamiton is the only antiscabies agent having antipruritic as well as antibacterial properties.[2] Topical crotamiton (10%) alone or with hydrocortisone (0.25%) have been successfully used in treating NS.[3]

One hundred cases of NS were diagnosed clinically and confirmed histopathologically from the Department of Skin and STD, Rajindra Hospital, Patiala from Feb. 95 to Dec, 96. After treating routine lesions of scabies, nodules in all the cases were treated with topical crotamiton (10%) with hydrocortisone (0.25%) applied thrice daily for 12 weeks. Out of 100 cases 78 showed partial regression of lesions at the end of second week. Complete regression of nodules occurred in 35/100 cases at the end of the 4th week, in 85/100 cases by the end of 6th week and in all the cases nodules disappeared by eighth week.

It was observed from the above study that topical ointment containing crotamiton and hydrocortisone application thrice daily is an excellent therapy for treating NS. Initial period of study was kept as 12 weeks, taking into consideration of intractable nature of NS; but all patients in the above study were cured by eighth week. So none of the cases needed intralesional steroids or excision of multiple nodules.

  References Top

1.Orkin M, Epstein E, Maibach HI. Treatment of today's scabies and pediculosis, JAMA 1976;236:1139.  Back to cited text no. 1  [PUBMED]  [FULLTEXT]
2.Cubela V, Yawalkar SJ. Clinical experience with crotamiton. Br J Clin Practice 1978;32:229-231.  Back to cited text no. 2    
3.Sharma VK, Kumar B. Persistent scabious nodules-A clinicopathologic study. Indian J Dermatol Venereol Leprol. 1986;52:26-29.  Back to cited text no. 3    


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