Indexed with PubMed and Science Citation Index (E) 
Users online: 4552 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
   Next article
   Previous article 
   Table of Contents
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   [PDF Not available] *
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

  In this article
   Case Report

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal


Year : 1997  |  Volume : 63  |  Issue : 5  |  Page : 310-311

Solitary mastocytoma in an adult

Correspondence Address:
V K Jain

Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 20944363

Rights and PermissionsRights and Permissions


A 24-year old female developed late onset solitary mastocytoma on the left forearm. She complained of intense pruritus off and on which was not associated with flushing of face and blister formation over the nodule. Darier's sign was positive. Excisional biopsy was done and histopathology confirmed the diagnosis.

Keywords: Mastocytosis, Flushing

How to cite this article:
Jain V K, Dayal S. Solitary mastocytoma in an adult. Indian J Dermatol Venereol Leprol 1997;63:310-1

How to cite this URL:
Jain V K, Dayal S. Solitary mastocytoma in an adult. Indian J Dermatol Venereol Leprol [serial online] 1997 [cited 2020 May 25];63:310-1. Available from: http://www.ijdvl.com/text.asp?1997/63/5/310/4602

Mastocytoma is a localized variety of mastocytosis which is characterized by appearance of red, pink or yellow nodules, usually solitary but occasionally multiple.[1] Lesions usually weal when rubbed and may be associated with vesiculation, blistering or attacks of flushing.[2] Local and systemic symptoms tend to diminish as the patients grow older.[3] Incidence of solitary mastocytosis has been estimated to be between 10 to 15 percent of patients with urticaria pigmentosa.[4] Solitary mastocytoma tends to involute spontaneously in 2 to 3 years. It is usually seen in infancy or childhood. Solitary mastocytoma with onset in adult is very rare and only a few cases have been reported in the world literature. [2,4-6]

  Case Report Top

A 24-year old female first noticed a slightly tender and itchy erythematous papule on left forearm. The lesion gradually increased in size to 1.5 cm in ten months. She used to have bouts of intense pruritus every 3-4 weeks. These bouts of pruritus were not associated with flushing of face and blister formation over the nodule. The lesion used to urticate with slight trauma. Initially, she was treated symptomatically with systemic anti-histamines and topical steroids with partial response. Later on, an excisional biopsy was done and histopathology of biopsy confirmed mast cell infiltration of the dermis.

  Discussion Top

In classification of mastocytosis, the term mastocytoma has been used to designate a patient with only one lesion. Solitary mastocytoma runs a benign course and has a tendency to regress. It has good prognosis in children.[7] Solitary mastocytoma in adults is rare. It is usually associated with vesiculation, blister or attacks of flushing.[3] Our patient had only solitary mastocytoma. Awareness of this rare condition in adults is important and by that more frequent recognition of this condition may be expected in the future. Treatment of solitary mastocytosis is usually completed by a simple excision as a diagnostic procedure.

  References Top

1.Greaves MW. The mastocytosis, in: Textbook of Dermatology, fourth ed, Editors, Rook A, Wilkinson D S, Ebling FJG, et al, Oxford University Press, India, 1992;1719-1726.  Back to cited text no. 1    
2.Birt AR, Nickerson M. Generalised flushing of the skin with urticaria pigmentosa. Arch Dermatol 1959;80:311-317.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Caplan RM. The natural course of urticaria pigmentosa. Arch Dermatol 1963;87:146-157.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]
4.Johnson WC, Helwig EM. Solitary mastocytosis (urticaria pigmentosa). Arch Dermatol 1961;64:806-815.  Back to cited text no. 4    
5.Baraf CS, Shapiro L. Solitary mastocytoma. Arch Dermatol 1969;99:589-590.  Back to cited text no. 5  [PUBMED]  [FULLTEXT]
6.Mittal RR, Goyal DK. Solitary mastocytoma in adults. Ind J Dermatol Venereol Leprol, 1990;56:315-316.  Back to cited text no. 6    
7.Holmber L. Solitary mastocytoma. Acta Paed Scand Uppsala 1970;59:558-590.  Back to cited text no. 7    


Print this article  Email this article
Previous article Next article


Online since 15th March '04
Published by Wolters Kluwer - Medknow