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CASE REPORT
Year : 1997  |  Volume : 63  |  Issue : 5  |  Page : 310-311

Solitary mastocytoma in an adult




Correspondence Address:
V K Jain


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Source of Support: None, Conflict of Interest: None


PMID: 20944363

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  Abstract 

A 24-year old female developed late onset solitary mastocytoma on the left forearm. She complained of intense pruritus off and on which was not associated with flushing of face and blister formation over the nodule. Darier's sign was positive. Excisional biopsy was done and histopathology confirmed the diagnosis.


Keywords: Mastocytosis, Flushing


How to cite this article:
Jain V K, Dayal S. Solitary mastocytoma in an adult. Indian J Dermatol Venereol Leprol 1997;63:310-1

How to cite this URL:
Jain V K, Dayal S. Solitary mastocytoma in an adult. Indian J Dermatol Venereol Leprol [serial online] 1997 [cited 2019 Aug 22];63:310-1. Available from: http://www.ijdvl.com/text.asp?1997/63/5/310/4602


Mastocytoma is a localized variety of mastocytosis which is characterized by appearance of red, pink or yellow nodules, usually solitary but occasionally multiple.[1] Lesions usually weal when rubbed and may be associated with vesiculation, blistering or attacks of flushing.[2] Local and systemic symptoms tend to diminish as the patients grow older.[3] Incidence of solitary mastocytosis has been estimated to be between 10 to 15 percent of patients with urticaria pigmentosa.[4] Solitary mastocytoma tends to involute spontaneously in 2 to 3 years. It is usually seen in infancy or childhood. Solitary mastocytoma with onset in adult is very rare and only a few cases have been reported in the world literature. [2,4-6]


  Case Report Top


A 24-year old female first noticed a slightly tender and itchy erythematous papule on left forearm. The lesion gradually increased in size to 1.5 cm in ten months. She used to have bouts of intense pruritus every 3-4 weeks. These bouts of pruritus were not associated with flushing of face and blister formation over the nodule. The lesion used to urticate with slight trauma. Initially, she was treated symptomatically with systemic anti-histamines and topical steroids with partial response. Later on, an excisional biopsy was done and histopathology of biopsy confirmed mast cell infiltration of the dermis.


  Discussion Top


In classification of mastocytosis, the term mastocytoma has been used to designate a patient with only one lesion. Solitary mastocytoma runs a benign course and has a tendency to regress. It has good prognosis in children.[7] Solitary mastocytoma in adults is rare. It is usually associated with vesiculation, blister or attacks of flushing.[3] Our patient had only solitary mastocytoma. Awareness of this rare condition in adults is important and by that more frequent recognition of this condition may be expected in the future. Treatment of solitary mastocytosis is usually completed by a simple excision as a diagnostic procedure.



 
  References Top

1.Greaves MW. The mastocytosis, in: Textbook of Dermatology, fourth ed, Editors, Rook A, Wilkinson D S, Ebling FJG, et al, Oxford University Press, India, 1992;1719-1726.  Back to cited text no. 1    
2.Birt AR, Nickerson M. Generalised flushing of the skin with urticaria pigmentosa. Arch Dermatol 1959;80:311-317.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Caplan RM. The natural course of urticaria pigmentosa. Arch Dermatol 1963;87:146-157.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]
4.Johnson WC, Helwig EM. Solitary mastocytosis (urticaria pigmentosa). Arch Dermatol 1961;64:806-815.  Back to cited text no. 4    
5.Baraf CS, Shapiro L. Solitary mastocytoma. Arch Dermatol 1969;99:589-590.  Back to cited text no. 5  [PUBMED]  [FULLTEXT]
6.Mittal RR, Goyal DK. Solitary mastocytoma in adults. Ind J Dermatol Venereol Leprol, 1990;56:315-316.  Back to cited text no. 6    
7.Holmber L. Solitary mastocytoma. Acta Paed Scand Uppsala 1970;59:558-590.  Back to cited text no. 7    




 

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