|Year : 1997 | Volume
| Issue : 2 | Page : 107-108
Murray williams warts
D Parsad, PK Sharma, RK Gautam, HK Kar
Source of Support: None, Conflict of Interest: None
A case of eruptive acanthoma also known as Murray Williams warts is being reported in a 35-year old male following contact allergic dermatitis to air borne allergens.
Keywords: Acanthoma, Murray Williams wart, Eczema
|How to cite this article:|
Parsad D, Sharma P K, Gautam R K, Kar H K. Murray williams warts. Indian J Dermatol Venereol Leprol 1997;63:107-8
| Introduction|| |
Eruptive acanthoma or Murray Williams wart had been repoted following resolution of inflammatory dermatosis. In 1956, Williams reported the appearance of these acanthoma after healing of various eczemas. The disease is primarily seen in older age group although a case had been reported in a 10 year old girl following sun burn reaction. [3,4] The disease tends to resolve in few months. The eruption consisted of papular warty lesions of variable sizes which make their appearance as the initial episode of eczema subsides.
| Case Report|| |
A 35-year-old male rickshaw puller, presented with complaints of itching, redness, oozing and scaling over face, neck, upper and lower extremities for 3 weeks. The eruption occurred almost simultaneously over all these areas. Similar episodes had been occurring over the past 3 years during the months of May, June and July. There was no history of atopy in the family. The cutaneous examination revealed erythema, oedema, mild oozing and scaling over face (including eyelids), neck, upper and lower extremities. The face, neck and cubital fossae were relatively more involved. Flat topped, skin coloured papules having an irregular surface appeared over dorsal and ventral surfaces of the upper and lower limbs and face, as the dermatitis started subsiding in about 4 week time. These warty papules varied in size from 4mm to 9mm. The lesions over the legs were more verrucous. The Koebner phenomenon was conspicuous.
The histopathology of the papular lesions revealed moderate hyperkeratosis, papillomatosis, acanthosis and at places circumscribed elevation of the epidermis resembling church spires. In the upper epidermis, neither vacuolisation nor horn cysts were observed.
| Discussion|| |
The episode of exogenous dermatitis due to air borne contactants followed by eruption of typical warty papules having characteristic histopathology which excluded viral aetiology made the diagnosis of eruptive acanthoma or Murray Williams warts. Perhaps the inflammatory dermatosis such as eczema acts as a stimulus to epidermal proliferation with resultant production of these acanthomas, as seen in this case as well. But the occurrence of these acanthomas only at certain portion of skin, remains a matter of speculation. The Koebner's phenomenon observed in this patient had not been reported earlier.
| References|| |
|1.||Griffiths WAD, Leigh IM, Marks R. Disorder of keratinization. In: Champion RH, Burton JL, Ebling FJG, editors. Textbook of dermatology. 5th edition. London: Blackwell Scientific Publication, 1992:1368. |
|2.||Williams MG. Acanthomata appearing after eczema. Br J Dermatol 1956;68:268-71. [PUBMED] |
|3.||Barriere H, Litoux P, Bureau, et al. Acanthomes post eczema. Bull Soc Fr Dermatol Syphiligr 1972;79:555-7. |
|4.||Fitzgerald DA, Stephens M, English JSC. Eruptive acanthoma following sunburn. Br J Dermatol 1995;133:493-4. |