|LETTER TO EDITOR
|Year : 1996 | Volume
| Issue : 3 | Page : 199
Alopecia areata in identical twins
Devraj Dogra, Apra Sood, K Binod Khaitan
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Dogra D, Sood A, Khaitan K B. Alopecia areata in identical twins. Indian J Dermatol Venereol Leprol 1996;62:199
| To the Editor,|| |
Two 28-year-old, identical twins developed alopecia areata (AA) of the beard region simultaneously 2½ years ago. Both had a lesion each, one had involvement of the right cheek, while the other had the lesion on the left cheek. The use of potent topical corticosteroid (fluocinolone acetonide 0.1%) led to complete regrowth of hair in both patients within 3 months. One of them developed a new lesion in the same location 3 months later which responded to same treatment again. The other patient developed a new lesion on the same side of the face 2 years later, which had shown partial regrowth of hair after 2 months of treatment with topical fluocinolone acetonide 0.1% Cutaneous examination revealed patchy hair loss with no skin atrophy or any other surface changes.
Detailed history revealed no stress factor that could have contributed to the development of alopecia in these patients. Neither of them had history of any other autoimmune disease.
The development of AA has been observed in several members of the same family. The incidence of family history of AA has been reported in upto 27% of the patients. There are only a few reports of AA occurring in identical twins. The occurrence of AA in the members of the same family especially in the identical twins, supports the hypothesis that the patients of AA are genetically predisposed to developing this disease.
| References|| |
|1.||Rook A, Dawber R. Diseases of hair and scalp. Oxford : Blackwell, 1982. |
|2.||Weidmann Al, Zion LS, Mamelok AE. Alopecia areata occurring simultaneously in identical twins. Arch Dermatol 1956;74:424-32. |
|3.||Cole GW, Herzhinger D. Alopecia universalis in identical twins. Int J Dermatol 1984;23:283. |
|4.||Scerri L, Pace JL. Identical twins with identical alopecia areata. J Am Acad Dermatol 1992;27:766. [PUBMED] |