IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 10309 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  NAVIGATE Here 
    Next article
    Previous article
    Table of Contents

 RESOURCE Links
    Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed8917    
    Printed138    
    Emailed5    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal

 

 SHORT COMMUNICATION
Year : 1996  |  Volume : 62  |  Issue : 2  |  Page : 91--94

A combination of amoxicillin and clavulanic acid in the treatment of pyoderma in children


Correspondence Address:
P K Kar


Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 20947990

Rights and PermissionsRights and Permissions

The efficacy and safety of amoxicillin plus clavulanic acid was compared with that of amoxicillin, erythromycin and co-trimoxazole in an open label, randomized trial in 50 children in each group (total 200) with mild to severe pyodermas. Majority (47%) had impetigo. Fifty (25%) children had mild pyoderma, 56 (28%) had moderate and 94 (47%) children had severe pyoderma. Pure growth of S aureus was isolated in 130 (65%) children, S pyogenes in 42 (21%) and both organisms in 28 (14%) children. In mild to moderate pyoderma either of the drug tried was equally effective. In severe pyoderma, 24 of twenty five (96%) children receiving amoxicillin plus clavulanic acid, 18 of twenty (90%) children in amoxicillin group, 20 of twenty four (83.3%) children in erythromycin group and 13 of twenty five (52%) children in co-trimoxazole group showed clinical cure of therapy. Amoxicillin combined with clavulanic acid was well tolerated in children and there was no significant side effect except mild diarrhoea in two cases (4%) which was well controlled by taking the drug with meals.






[FULL TEXT] [PDF Not available]*


        
Print this article     Email this article

Online since 15th March '04
Published by Wolters Kluwer - Medknow